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The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the unfolded protein response (UPR). The UPR enhances production of ER-resident chaperones and enzym ...
In almost all bacteria, cell division is co-ordinated by the essential tubulin homologue FtsZ and represents an attractive but as yet unexploited target for new antibiotics. The benzamides, e.g. PC190723, are potent FtsZ inhibitors that have the potential ...
Recently, several studies have demonstrated that tetracyclines, the antibiotics most intensively used in livestock and that are also widely applied in biomedical research, interrupt mitochondrial proteostasis and physiology in animals ranging from round wo ...
The planktonic foraminifera Orbulina universa is living in the photic zone of marine water columns and it possesses photosynthetic microalgae symbionts in its cytoplasm (dinoflagellates). The transfer of carbon compounds from the symbiotic microalgae to th ...
Despite recent advances in down-stream processing, production of microalgae remains substantially limited because of economical reasons. Harvesting and dewatering are the most energy-intensive processing steps in their production and contribute 20–30% of t ...
Microsecond molecular dynamics simulations of B-DNA oligomers carried out in an aqueous environment with a physiological salt concentration enable us to perform a detailed analysis of how potassium ions interact with the double helix. The oligomers studied ...
Thylakoids are the photosynthetic membranes in chloroplasts and cyanobacteria. The aqueous phase inside the thylakoid known as the thylakoid lumen plays an essential role in the photosynthetic electron transport. The presence and significance of thiol-disu ...
Nanoparticles have various physicochemical properties attributed by their small dimensions. The global production of nanoparticles lead to a raised concern for their environmental impacts. Algae are of highly ecological importance functioning as primary pr ...
Green plant Photosystem II (PSII) and light-harvesting complex II (LHCLI) in the stacked grana regions of thylakoid membranes can self-organize into various PSII LHCII supercomplexes With crystalline Of fluid-like supramolecular structures to adjust themse ...
Under aerobic conditions, excessive illumination results in the photogeneration of reactive oxygen species (ROS) responsible for protein damage and photo-inhibition during photosynthesis. We explore the effects of nanoceria (NC), a regenerative ROS scaveng ...