Concept

Olfactory receptor neuron

Publications associées (69)

How good Gestalt determines low level vision

In classical models of vision, low level visual tasks are explained by low level neural mechanisms. For example, in crowding, perception of a target is impeded by nearby elements because, as it is argued, responses of neurons coding for nearby elements are ...

Pion Ltd.2012

Recombinant expression and functional characterization of the mouse olfactory receptor mOR256-17 in mammalian cells

Horst Vogel, Horst Pick, Luigino Grasso, Thamani Dahoun

Olfactory receptors (ORs) constitute the largest family of sensory membrane proteins in mammals. They play a key role within the olfactory system in recognizing and discriminating a nearly unlimited number of structurally diverse odorous molecules. The mol ...

2011

The Mouse Eugenol Odorant Receptor: Structural and Functional Plasticity of a Broadly Tuned Odorant Binding Pocket

Horst Vogel, Horst Pick, Olivia Baud, Sylvain Etter

Molecular interactions of odorants with their olfactory receptors (ORs) are of central importance for the ability of the mammalian olfactory system to detect and discriminate a vast variety of odors with a limited set of receptors. How a particular OR bind ...

American Chemical Society2011

Gamma-Secretase Dependent Gene Expression

Alexandra Marie-Isabelle Karoline Brigitte Magold

The causes of sporadic Alzheimer's Disease (AD), the most common form of dementia at old age, are still unknown. Familial early onset AD (FAD) is mainly caused by mutations of Presenilins (PS), the active subunits of γ-secretase. Processing of its substrat ...

EPFL2011

Complementary Function and Integrated Wiring of the Evolutionarily Distinct Drosophila Olfactory Subsystems

Pavan P Ramdya

To sense myriad environmental odors, animals have evolved multiple, large families of divergent olfactory receptors. How and why distinct receptor repertoires and their associated circuits are functionally and anatomically integrated is essentially unknown ...

2011

Evolving olfactory systems on the fly

Pavan P Ramdya

The detection of odour stimuli in the environment is universally important for primal behaviours such as feeding, mating, kin interactions and escape responses. Given the ubiquity of many airborne chemical signals and the similar organisation of animal olf ...

2010

Emergent Dynamics in Neocortical Microcircuits

Rodrigo de Campos Perin

Interactions among neurons can take place in a wide variety of forms. It is the goal of this thesis to investigate the properties and implications of a number of these interactions that we believe are relevant for information processing in the brain. Neuro ...

EPFL2010

On the identification of sensory information from mixed nerves by using single-channel cuff electrodes

Silvestro Micera, Stanisa Raspopovic

Background: Several groups have shown that the performance of motor neuroprostheses can be significantly improved by detecting specific sensory events related to the ongoing motor task (e. g., the slippage of an object during grasping). Algorithms have bee ...

2010

Bioanalytical procedure to detect membrane receptor activation

Horst Vogel, Horst Pick

The invention concerns a method for screening compound interaction with transmembrane receptors involved in cellular signal transduction, preferably with G protein coupled receptors, by adding the compound to be analyzed into a medium comprising native inv ...

2010

Dual activities of odorants on olfactory and nuclear hormone receptors

Horst Vogel, Horst Pick, Olivia Baud, Sylvain Etter, Ralf Schmauder

We have screened an odorant compound library and discovered molecules acting as chemical signals that specifically activate both G-protein-coupled olfactory receptors (ORs) on the cell surface of olfactory sensory neurons and the human nuclear estrogen rec ...

American Society for Biochemistry and Molecular Biology2009

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