Concept
Rétrécissement mitral
Publications associées (32)
The Impact of Left Ventricular Performance and Afterload on the Evaluation of Aortic Valve Stenosis: A 1D Mathematical Modeling Approach
The transaortic valvular pressure gradient (TPG) plays a central role in decision-making for patients suffering from severe aortic stenosis. However, the flow-dependence nature of the TPG makes the diagnosis of aortic stenosis challenging since the markers ...
MDPI2023Hemodynamic effects of a dielectric elastomer augmented aorta on aortic wave intensity: An in-vivo study
Yves Perriard, Yoan René Cyrille Civet, Thomas Guillaume Martinez, Francesco Clavica, Armando Matthieu Walter, Silje Ekroll Jahren, Lorenzo Ferrari
Dielectric elastomer actuator augmented aorta (DEA) represents a novel approach with high potential for assisting a failing heart. The soft tubular device replaces a section of the aorta and increases its diameter when activated. The hemodynamic interactio ...
2023Finding information-rich electrocardiographic biomarkers to characterize atrial fibrillation.
Atrial fibrillation (AF) is the most common cardiac arrhythmia; it will affect one in four adults worldwide in their lifetime. AF has serious consequences, including drastically increased risk of stroke. Catheter ablation surgery is an established treatmen ...
EPFL2023Prognostic Implications of the Novel Pulmonary Hypertension Definition in Patients with Aortic Stenosis after Transcatheter Valve Replacement
Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou
Introduction: Pulmonary hypertension (PH), traditionally defined as a mean pulmonary artery pressure (PAP) >= 25 mmHg, is associated with poor outcomes in patients undergoing a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS). ...
MDPI2022Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure
Yi Zhang, Annina Stuber, Ashish Gupta
BACKGROUND: Abnormalities in cardiac energy metabolism occur in heart failure (HF) and contribute to contractile dysfunction, but their role, if any, in HF-related pathologic remodeling is much less established. CK (creatine kinase), the primary muscle ene ...
LIPPINCOTT WILLIAMS & WILKINS2022Cell administration routes for heart failure: a comparative re-evaluation of the REGENERATE-DCM and REGENERATE-IHD trials
Aims: Given the logistical issues surrounding intramyocardial cell delivery, we sought to address the efficacy of the simpler, more accessible intracoronary route by re-evaluating REGENERATE-DCM and REGENERATE-IHD (autologous cell therapy trials for heart ...
FUTURE MEDICINE LTD2022A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation
Alfio Quarteroni, Andrea Manzoni
In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain the long-debated mechanisms behind atrial fibrillation (AF) and to reliably numerically predict its induction and sustainment. A key role is pla ...
FRONTIERS MEDIA SA2021