Chemokine receptor

Résumé

Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine. There have been 20 distinct chemokine receptors discovered in humans. Each has a rhodopsin-like 7-transmembrane (7TM) structure and couples to G-protein for signal transduction within a cell, making them members of a large protein family of G protein-coupled receptors. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium (Ca2+) ions (calcium signaling). This causes cell responses, including the onset of a process known as chemotaxis that traffics the cell to a desired location within the organism. Chemokine receptors are divided into different families, CXC chemokine receptors, CC chemokine receptors, CX3C chemokine receptors and XC chemokine receptors that correspond to the 4 distinct subfamilies of chemokines they bind. Four families of chemokine receptors differ in spacing

Source officielle

https://en.wikipedia.org/wiki/Chemokine_receptor

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Chemokine receptor

Contemporary evaluation of T cell subsets, chemokine receptors expression, cytokine production, anti-HIV cytotoxic activity and TCR V-beta repertoire in HIV-1-infected individuals during HAART

Contemporary evaluation of T cell subsets, chemokine receptors expression, cytokine production, anti-HIV cytotoxic activity and TCR V-beta repertoire in HIV-1-infected individuals during HAART

T cell responses to highly active antiretroviral therapy defined by chemokine receptors expression, cytokine production, T cell receptor repertoire and anti-HIV T-lymphocyte activity

T cell responses to highly active antiretroviral therapy defined by chemokine receptors expression, cytokine production, T cell receptor repertoire and anti-HIV T-lymphocyte activity

Contemporary evaluation of T cell subsets, chemokine receptors expression, cytokine production, anti-HIV cytotoxic activity and TCR V-beta repertoire in HIV-1-infected individuals during HAART

Contemporary evaluation of T cell subsets, chemokine receptors expression, cytokine production, anti-HIV cytotoxic activity and TCR V-beta repertoire in HIV-1-infected individuals during HAART