Publications associées à Anesthetic

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Grégoire Courtine, Eduardo Martin Moraud, Tomislav Milekovic, Shiqi Sun

Parkinson's disease motor symptoms are treated with levodopa, but long‐term treatment leads to disabling dyskinesia. Altered synaptic transmission and maladaptive plasticity of corticostriatal glutamatergic projections play a critical role in the pathophys ...

2018

Dynamic reorganization of intrinsic functional networks in the mouse brain

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Maria Giulia Preti, Joanes Grandjean, Markus Rudin

Functional connectivity (FC) derived from resting-state functional magnetic resonance imaging (rs-fMRI) allows for the integrative study of neuronal processes at a macroscopic level. The majority of studies to date have assumed stationary interactions betw ...

Elsevier2017

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Barbiturates, commonly used as general anaesthetics, depress neuronal activity and thus cerebral metabolism. Moreover, they are likely to disrupt the metabolic support of astrocytes to neurons, as well as the uptake of nutrients from circulation. By employ ...

Wiley-Blackwell2017

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics

Kristin Schirmer, Julita Maria Stadnicka-Michalak

Zebrafish (Danio rerio) larvae have been suggested as vertebrate model to complement or even replace mammals for rapidly assessing behavioral effects of psychoactive drugs. Yet, divergent responses have been reported in mammals and fish despite the conserv ...

Oxford Univ Press2016

Optimization of drug combinations using Feedback System Control

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska

We describe a protocol for the discovery of synergistic drug combinations for the treatment of disease. Synergistic drug combinations lead to the use of drugs at lower doses, which reduces side effects and can potentially lead to reduced drug resistance, w ...

Nature Publishing Group2016

A streamlined search technology for identification of synergistic drug combinations

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska

A major key to improvement of cancer therapy is the combination of drugs. Mixing drugs that already exist on the market may offer an attractive alternative. Here we report on a new model-based streamlined feedback system control (s-FSC) method, based on a ...

Nature Publishing Group2015

Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Sequential Kharasch–Dehalogenation Reactions

Kay Severin, Julie Risse, Yanouk Cudré

A two-step process for the synthesis of trifluoromethyl-substituted cyclopropanes is described. Halothane, an anesthetic agent, is added to olefins in a ruthenium-catalyzed Kharasch reaction. The resulting 1,3-dihalides are converted into cyclopropanes by ...

American Chemical Society2012

Automatic Mallampati Classification Using Active Appearance Models

Jean-Philippe Thiran, Matteo Sorci, Anil Yuce, Gabriel Louis Cuendet

Difficult tracheal intubation assessment is an important research topic in anesthesia as failed intubations are important causes of mortality in anesthetic practice. The modified Mallampati score is widely used, alone or in conjunction with other criteria, ...

2012

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Anesthetic

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Dynamic reorganization of intrinsic functional networks in the mouse brain

Xenon Recovery at Room Temperature using Metal-Organic Frameworks

Energy metabolism in the rat cortex under thiopental anaesthesia measured

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics

Optimization of drug combinations using Feedback System Control

A streamlined search technology for identification of synergistic drug combinations

Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Sequential Kharasch–Dehalogenation Reactions

Automatic Mallampati Classification Using Active Appearance Models

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

Graph Chatbot

Chattez avec Graph Search

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Sequential Kharasch–Dehalogenation Reactions

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics

Dynamic reorganization of intrinsic functional networks in the mouse brain

Xenon Recovery at Room Temperature using Metal-Organic Frameworks

Optimization of drug combinations using Feedback System Control

Energy metabolism in the rat cortex under thiopental anaesthesia measured

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

A streamlined search technology for identification of synergistic drug combinations

Automatic Mallampati Classification Using Active Appearance Models