Concept

Résistance vasculaire

Publications associées (127)

Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction

We present use of a synthetic, injectable matrix metalloproteinase (MMP)- responsive, bioactive hydrogel as an in situ forming scaffold to deliver thymosin beta 4 (T beta 4), a pro-angiogenic and pro-survival factor, along with vascular cells derived from ...

2011

Role of Jagged1 in Arterial Lesions After Vascular Injury

Freddy Radtke, Qi Zhou, Hui Gong

Objective-Impaired regeneration of endothelial cells (EC) and overactivity of vascular smooth muscle cells (VSMC) are hallmarks of the arterial lesions associated with aging. The occurrence of 2 opposing cellular processes in the same arterial milieu makes ...

American Heart Association2011

Propagation of fast and slow intercellular Ca2+ waves in primary cultured arterial smooth muscle cells

Jean-Jacques Meister, Jean-Louis Bény, Nadia Halidi

Smooth muscle contraction is regulated by changes in cytosolic Ca2+ concentration (Ca2+). In response to stimulation, Ca2+ increase in a single cell can propagate to neighbouring cells through gap junctions, as intercellular Ca2+ waves. To investigate ...

2011

Geometrical multiscale model of an idealized left ventricle with fluid-structure interaction effects coupled to a one-dimensional viscoelastic arterial network

Simone Deparis, Toni Mikael Lassila, Adelmo Cristiano Innocenza Malossi

A geometrical multiscale model for blood flow through an ideal left ventricle and the main arteries is presented. The blood flow in the three-dimensional idealized left ventricle is solved through a monolithic fluid-structure interaction solver. To account ...

2011

Identification and functional response of interstitial Cajal-like cells from rat mesenteric artery

Jean-Jacques Meister, Jean-Louis Bény, Lara Buscemi Estefanell, Aurélie Formey de Saint Louvent

Cells with irregular shapes, numerous long thin filaments, and morphological similarities to the gastrointestinal interstitial cells of Cajal (ICCs) have been observed in the wall of some blood vessels. These ICC-like cells (ICC-LCs) do not correspond to t ...

Springer-Verlag2011

A structural constitutive model considering angular dispersion and waviness of collagen fibres of rabbit facial veins

Nikolaos Stergiopoulos, Aristotelis Agianniotis

Background: Structural constitutive models of vascular wall integrate information on composition and structural arrangements of tissue. In blood vessels, collagen fibres are arranged in coiled and wavy bundles and the individual collagen fibres have a devi ...

BioMed Central2011

Capillary Microfluidic Chips for Point-of-Care Testing

Luc Gervais

Research on microfluidic devices for biological analysis has progressed sufficiently to be developed into point-of-care diagnostics products. The goal of this thesis is to improve multiple aspects of capillary-driven microfluidic devices. In particular, th ...

EPFL2011

Efficient Solution of Fluid-Structure Interaction Problems in Computational Hemodynamics

Alfio Quarteroni, Simone Deparis, Paolo Crosetto

Cardiovascular diseases are the first cause of death in industrialized countries. It is now widely established that blood fluid dynamics and its interaction with the vascular wall play an essential role in the development and evolution of vascular patholog ...

American Institute of Physics2010

Biomechanics of Vascular Wall

Rana Saitta-Rezakhaniha

This thesis contributes to the field of biomechanics of vascular wall. The focus is particularly on the microstructure of vascular elastin and collagen constituents and their contribution to the macroscopic mechanical behavior of the wall. The analysis is ...

EPFL2010

Arterial remodeling using a constituent-based approach

Alkiviadis Tsamis

This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...

EPFL2010

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