Concept

3,4-Méthylènedioxyamphétamine

Publications associées (9)

Shared functional connectome fingerprints following ritualistic ayahuasca intake

Enrico Amico, Hanna Tolle, Pablo Mallaroni

The knowledge that brain functional connectomes are unique and reliable has enabled behaviourally relevant inferences at a subject level. However, whether such "fingerprints" persist under altered states of consciousness is unknown. Ayahuasca is a potent s ...

San Diego2023

A Biochemical and Biophysical Investigation of 5-HT3 Receptor Stability

Menno Berend Tol

The 5-hydroxytryptamine 3 receptor (5-HT3R) is a member of the pentameric ligand-gated ion channel (pLGIC) family, that plays an important role in fast signal transduction and cell-cell communication in synapses: They convert a chemical signal from a neuro ...

EPFL2012

Enhanced light harvesting in mesoporous TiO2/P3HT hybrid solar cells using a porphyrin dye

Michael Graetzel, Shaik Mohammed Zakeeruddin, Kevin Sivula, Soo-Jin Moon

We report panchromatic light harvesting in hybrid TiO2/P3HT photovoltaic devices using a porphyrin dye that complements the light absorption of P3HT. The high short circuit photocurrent (12.1 mA cm(-2)) obtained is found to be due, in part, to Forster reso ...

2011

Ultrafast spectroscopic investigation of a fullerene poly(3-hexylthiophene) dyad

Natalie Renuka Banerji, Eric Vauthey

We present the femtosecond spectroscopic investigation of a covalently linked dyad, PCB-P3HT, formed by a segment of the conjugated polymer P3HT (regioregular poly(3-hexylthiophene)) that is end capped with the fullerene derivative PCB ([6,6]-phenyl-C-61-b ...

2011

Free operant and discrete trial performance of mice in the nine-hole box apparatus: validation using amphetamine and scopolamine

Jean-Charles Bensadoun

RATIONALE: To determine the suitability of the nine-hole box to characterise mouse performance on a free operant task and a discrete trials task, and to validate the tests by probing whether d-amphetamine and scopolamine modify performance of the task as p ...

2004

Noninvasive imaging of 5-HT3 receptor trafficking in live cells: From biosynthesis to endocytosis

Horst Vogel, Horst Pick, Cédric Deluz, Erwin Ilegems

Sequential stages in the life cycle of the ionotropic 5-HT3 receptor (5-HT3R) were resolved temporally and spatially in live cells by multicolor fluorescence confocal microscopy. The insertion of the enhanced cyan fluorescent protein into the large intrace ...

2004

Characterization of the Ligand-binding Site of the Serotonin 5-HT3 Receptor: The Role of Glutamate Residues 97, 224,and 235

Horst Vogel, Rudolf Hovius, Horst Pick, Christoph Schreiter, Matteo Costioli

Ligand-gated ion channels of the Cys loop family are receptors for small amine-contg. neurotransmitters. Charged amino acids are strongly conserved in the ligand-binding domain of these receptor proteins. To investigate the role of particular residues in l ...

2003

The trifluoromethoxy group:- a long-range electron-withdrawing substituent

Judged by its capacity to promote a hydrogen/metal permutation at an ortho position, the trifluoromethoxy group is superior to both the methoxy and trifluoromethyl groups. Moreover, like CF3 and unlike OCH3, OCF3 exerts a long-range effect that still consi ...

2002

Ligand binding to the serotonin 5HT3 receptor studied with a novel fluorescent ligand

Horst Vogel, Rudolf Hovius, Horst Pick, Alain Bernard

The thermodn. and kinetics of ligand binding to the purified serotonin 5HT3 receptor and the local environment of the bound ligand were studied by fluorescence spectroscopy using a novel fluorescein-labeled ligand GR-flu [1,2,3,9-tetrahydro-3-[(5-methyl-1H ...

1998

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