Publications associées à Cancer des voies aérodigestives supérieures

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Inhibition of P-glycoprotein (P-gp) transporter is an attractive approach for the reversion of cancer-associated multidrug resistance (MDR). Poly(N-(2-hydroxypropyl) methacrylamide) (PHPMA)-based carriers that are able to release the anticancer drug doxoru ...

2017

Microenvironmental regulation of tumour angiogenesis

Michele De Palma, Daniela Biziato

Tumours display considerable variation in the patterning and properties of angiogenic blood vessels, as well as in their responses to anti-angiogenic therapy. Angiogenic programming of neoplastic tissue is a multidimensional process regulated by cancer cel ...

Nature Publishing Group2017

TOWARD THE IDENTIFICATION OF NEW CANCER THERAPY TARGETS USING METABOLIC MODELING IN A HUMAN GENOME SCALE

Vassily Hatzimanikatis, Meriç Ataman, Georgios Fengos, Maria Masid Barcon

Cancer is a leading cause of death in the world, and the mechanisms that underlie this disease are still not completely understood. In the last decades, altered tumor metabolism has been recognized as one of the hallmarks of cancer. Modeling the different ...

2017

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

Maartje Martina Cornelia Bastings

Immunogenic subcellular vesicular particles that can be used to stimulate antigen-specific immune responses in vitro and in vivo are generated from whole cancer cells. The particles retain a broad antigen repertoire similar to that of the parent cells, and ...

Wiley-Blackwell2016

Piezoresistive Membrane Surface Stress Sensors for Characterization of Breath Samples of Head and Neck Cancer Patients

Terunobu Akiyama, Frédéric Loizeau, Pedro Romero, Christoph Gerber

For many diseases, where a particular organ is affected, chemical by-products can be found in the patient's exhaled breath. Breath analysis is often done using gas chromatography and mass spectrometry, but interpretation of results is difficult and time-co ...

Mdpi Ag2016

Dinuclear arene ruthenium thiolato complexes with fluorous side-chains

Paul Joseph Dyson, Tina Riedel

Four complexes of the general formula (eta(6)-p-MeC6H4Pri)(2)Ru-2(mu-SC2H4R)(3), R = (CF2)(7)CF3 (1), (CF2)(5)CF3 (2), (CF2)(3)CF3 (3) and (CH2)(5)CH3 (4) were synthesized and characterized. The molecular structures of complexes 1 and 3 were confirmed ...

Elsevier Science Sa2016

Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors

Anne Planche, Tania Santoro

Background: Blocking the mechanistic target of rapamycin complex-1 (mTORC1) with chemical inhibitors such as rapamycin has shown limited clinical efficacy in cancer. The tumor microenvironment is characterized by an acidic pH which interferes with cancer t ...

Biomed Central Ltd2016

Cytotoxic double arene ruthenium metalla-cycles that overcome cisplatin resistance

Paul Joseph Dyson, Mylène Soudani, Tina Riedel

Tetranuclear arene ruthenium complexes of the general formula {Ru-2(p-cymene)(2)(mu(4)-L)}(2)(mu(4)-tpom) (tpom = tetrakis(4-pyridyloxymethylene)methane) were obtained from the corresponding dinuclear arene ruthenium complexes [Ru-2(p-cymene)(2)(m(4) ...

Elsevier Science Sa2016

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Cancer des voies aérodigestives supérieures

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Microenvironmental regulation of tumour angiogenesis

TOWARD THE IDENTIFICATION OF NEW CANCER THERAPY TARGETS USING METABOLIC MODELING IN A HUMAN GENOME SCALE

Group Decisions Influence Emergence and Regulation of Leaders during Collective Migration of Epithelial Cells

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

Piezoresistive Membrane Surface Stress Sensors for Characterization of Breath Samples of Head and Neck Cancer Patients

Prediction of occult lymph node metastasis in squamous cell carcinoma of the oral cavity and the oropharynx using peritumoral Prospero homeobox protein 1 lymphatic nuclear quantification

Dinuclear arene ruthenium thiolato complexes with fluorous side-chains

Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors

Cytotoxic double arene ruthenium metalla-cycles that overcome cisplatin resistance

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Chattez avec Graph Search

Prediction of occult lymph node metastasis in squamous cell carcinoma of the oral cavity and the oropharynx using peritumoral Prospero homeobox protein 1 lymphatic nuclear quantification

Microenvironmental regulation of tumour angiogenesis

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Group Decisions Influence Emergence and Regulation of Leaders during Collective Migration of Epithelial Cells

TOWARD THE IDENTIFICATION OF NEW CANCER THERAPY TARGETS USING METABOLIC MODELING IN A HUMAN GENOME SCALE

Piezoresistive Membrane Surface Stress Sensors for Characterization of Breath Samples of Head and Neck Cancer Patients

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

Cytotoxic double arene ruthenium metalla-cycles that overcome cisplatin resistance

Dinuclear arene ruthenium thiolato complexes with fluorous side-chains

Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors