Publications associées à Chimiotaxie

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Jean-Jacques Meister, Chiara Gabella, Franck Claude Raynaud, Alicia Carine Bornert

How cells break symmetry and organize activity at their edges to move directionally is a fundamental question in cell biology. Physical models of cell motility commonly incorporate gradients of regulatory proteins and/or feedback from the motion itself to ...

Nature Publishing Group2016

Microfluidic co-culture platform to quantify chemotaxis of primary stem cells

Zuzana Tatárová

Functional analysis of primary tissue-specific stem cells is hampered by their rarity. Here we describe a greatly miniaturized microfluidic device for the multiplexed, quantitative analysis of the chemotactic properties of primary, bone marrow-derived mese ...

Royal Soc Chemistry2016

Fundamental Constraints on the Abundances of Chemotaxis Proteins

Anne-Florence Raphaëlle Bitbol

Flagellated bacteria, such as Escherichia coli, perform directed motion in gradients of concentration of attractants and repellents in a process called chemotaxis. The E. coli chemotaxis signaling pathway is a model for signal transduction, but it has uniq ...

Elsevier BV2015

Three-dimensional chemotaxis-driven aggregation of tumor cells

Alessandro De Simone, Andrea Gamba

One of the most important steps in tumor progression involves the transformation from a differentiated epithelial phenotype to an aggressive, highly motile phenotype, where tumor cells invade neighboring tissues. Invasion can occur either by isolated mesen ...

Nature Publishing Group2015

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa

Alexandre Louis André Persat, Joanne Netter Engel

Bacteria have evolved a wide range of sensing systems to appropriately respond to environmental signals. Here we demonstrate that the opportunistic pathogen Pseudomonas aeruginosa detects contact with surfaces on short timescales using the mechanical activ ...

2015

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Eleonora Simeoni, Jeffrey Alan Hubbell, David Scott Wilson, Martina Damo

Dendritic cell (DC)-derived exosomes (Dexo) contain the machinery necessary to activate potent antigen-specific immune responses. As promising cell-free immunogens, Dexo have been tested in previous clinical trials for cancer vaccine immunotherapy, yet res ...

Nature Publishing Group2015

Bioluminescence imaging of small biomolecules

Aurélien Godinat, Riccardo Sinisi, Grigory Karateev, Ghyslain Martial Alain Budin, Aleksandra Konovalova, Jens Tomas Frigell

The invention relates to a technique to detect small molecules using Bioluminescence imaging (BLI) to image and quantify non-invasively, in vitro and in vivo,intracellular metabolite fluxes and which can be applied to azido-modified compounds, such as azid ...

2014

Cell shape-dependent early responses of fibroblasts to cyclic strain

Jürgen Brugger, Mattia Marelli

Randomly spread fibroblasts on fibronectin-coated elastomeric membranes respond to cyclic strain by a varying degree of focal adhesion assembly and actin reorganization. We speculated that the individual shape of the cells, which is linked to cytoskeletal ...

Elsevier2013

Cooperative Roles of SDF-1 alpha and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Melody Swartz, Mingming Wu

Chemokine-mediated directed tumor cell migration within a three dimensional (3D) matrix, or chemoinvasion, is an important early step in cancer metastasis. Despite its clinical importance, it is largely unknown how cytokine and growth factor gradients with ...

Public Library of Science2013

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Chimiotaxie

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Microfluidic co-culture platform to quantify chemotaxis of primary stem cells

Development of microfluidic devices for chemotaxis of primary stem cells

Fundamental Constraints on the Abundances of Chemotaxis Proteins

Three-dimensional chemotaxis-driven aggregation of tumor cells

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Bioluminescence imaging of small biomolecules

Cell shape-dependent early responses of fibroblasts to cyclic strain

Cooperative Roles of SDF-1 alpha and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Graph Chatbot

Chattez avec Graph Search

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Three-dimensional chemotaxis-driven aggregation of tumor cells

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Fundamental Constraints on the Abundances of Chemotaxis Proteins

Bioluminescence imaging of small biomolecules

Microfluidic co-culture platform to quantify chemotaxis of primary stem cells

Development of microfluidic devices for chemotaxis of primary stem cells

Cell shape-dependent early responses of fibroblasts to cyclic strain

Cooperative Roles of SDF-1 alpha and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model