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Derme

Publications associées (32)

Printed Iontophoretic‐Integrated Wearable Microfluidic Sweat‐Sensing Patch for On‐Demand Point‐Of‐Care Sweat Analysis

Danick Briand, Silvia Demuru, Brince Paul Kunnel

In recent years, wearable epidermal sweat sensors have received extensive attention owing to their great potential to provide personalized information on the health status of individuals at the molecular level. For on‐demand medical analysis of sweat in se ...

2021

Spontaneous formation of ordered micro-wrinkles on a thermosensitive resist

Jürgen Brugger, Giovanni Boero, Xia Liu, Ana Conde Rubio, Mohammadreza Rostami

Self-organizing patterns with micrometer-scale features are promising for applications in photonics and bioengineering. Their spontaneous formation reduces the number of required processing steps. Here, we report an approach to spontaneously form stochasti ...

2021

Single-cell lipidomics reveals a role for cell-to-cell sphingolipid heterogeneity in fibroblast activation

Laura Capolupo

Cell-to-cell variability plays a key role in tissue patterning by setting initial asymmetry that primes cell fate decisions. Fluctuations in the activity of regulatory molecules can commit individual cells to divergent differentiation pathways, and cell-to ...

EPFL2021

A new paradigm for leprosy diagnosis based on host gene expression

Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Thyago Leal Calvo

Author summary Despite effective treatment, leprosy is still a significant public health issue in more than 120 countries, with more than 200 000 new cases yearly. The disease is caused mainly by Mycobacterium leprae, a slow-growing bacillus still uncultiv ...

PUBLIC LIBRARY SCIENCE2021

Skin cell analysis

Hubert Girault, Horst Pick, Andreas Stephan Lesch, Milica Jovic, Tzu-En Lin, Yingdi Zhu

The present invention describes an adhesive tape stripping transfer method for quick and non-invasive diagnosis of skin diseases by MALDI-TOF mass spectrometry analysis. Cells from the epidermis layer of a suspicious skin area of a patient are collected us ...

2020

The Delivery of alpha 1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore

Florian Maria Wurm

Human alpha 1-antitrypsin (AAT) is an abundant acute phase glycoprotein expressing anti-protease and immunomodulatory activities, and is used as a biopharmaceutical to treat patients with inherited AAT deficiency. The pleiotropic properties of AAT provide ...

FRONTIERS MEDIA SA2020

Method and system for analysis of organic material by auto-cathodoluminescence

Hans Mattias Larsson

Analyzing isolated collagen gel samples of a rat-tail and bovine hide, we demonstrated in situ detection of spectrally deconvoluted auto-cathodoluminescence signatures of specific molecular content with precise spatial localization over a maximum field of ...

2020

From the early steps of whisker formation to its evolutionary disappearance: the (curious) case of Prdm1 and its regulation

Pierluigi Giuseppe Manti

Whiskers (also known as vibrissae) are sensory organs that are thought to have first appeared in Therapsida, a group of synapsids that includes mammals and evolutionary ancestors like the Thrinaxodon(1). They are highly conserved among mammals to the notab ...

EPFL2016

Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment

Kristin Schirmer

This paper reports the first successful derivation and characterization of humpback whale fibroblast cell lines. Primary fibroblasts were isolated from the dermal connective tissue of skin biopsies, cultured at 37 degrees C and 5% CO2 in the standard mamma ...

Elsevier Science Bv2015

Motor Control in the Mouse Whisker System

Varun Sreenivasan

The motor systems of the mammalian brain are a remarkable product of many millions of years of evolution. It is the motor systems that make us and other mammals mobile, that guide our actions in response to sensory information and conversely modulate the v ...

EPFL2015

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