Publications associées à Caenorhabditis briggsae

Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos

Whereas both sperm and egg contribute nuclear genetic material to the zygote in metazoan organisms, the inheritance of other cellular constituents is unequal between the 2 gametes. Thus, 2 copies of the centriole are contributed solely by the sperm to the ...

GENETICS SOCIETY AMERICA2023

High-resolution imaging and analysis of the intestinal bacterial load of Caenorhabditis elegans during early adulthood

Martinus Gijs, Farzad Rezaeianaran

We study the presence within the worm Caenorhabditis elegans (C. elegans) of a fluorescent strain of the worm's bacterial food (Escherichia coli (E. coli) OP50) during early adulthood. Use of a microfluidic chip based on a thin glass coverslip substrate al ...

ROYAL SOC CHEMISTRY2023

Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS-1

Pierre Gönczy, Coralie Busso, Alexander Woglar, Keshav Jha, Tamara Mikeladze-Dvali, Marie Juliette Ségolène Pierron

In most metazoans, centrioles are lost during oogenesis, ensuring that the zygote is endowed with the correct number of two centrioles, which are paternally contributed. How centriole architecture is dismantled during oogenesis is not understood. Here, we ...

Hoboken2023

Deformation-aware Unpaired Image Translation for Pose Estimation on Laboratory Animals

Pascal Fua, Pavan P Ramdya, Helge Jochen Rhodin, Semih Günel, Siyuan Li, Mirela Ostrek

Our goal is to capture the pose of neuroscience model organisms, without using any manual supervision, to be able to study how neural circuits orchestrate behaviour. Human pose estimation attains remarkable accuracy when trained on real or simulated datase ...

2020

Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform

Martinus Gijs, Matteo Cornaglia, Raphaël Etienne Jean Trouillon, Hüseyin Baris Atakan, Tunç Alkanat

The nematode Caenorhabditis elegans has been extensively used as a model multicellular organism to study the influence of osmotic stress conditions and the toxicity of chemical compounds on developmental and motility-associated phenotypes. However, the sev ...

2020

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Johan Auwerx, Hilal Lashuel, Laurent Mouchiroud, Lara Petricca, Anass Chiki, Ramanath Narayana Hegde

Phosphorylation of the N‐terminal domain of the huntingtin (HTT ) protein has emerged as an important regulator of its localization, structure, aggregation, clearance and toxicity. However, validation of the effect of bona fide phosphorylation in vivo and ...

2020

Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

Johan Auwerx, Martinus Gijs, Matteo Cornaglia, Laurent Mouchiroud, Elena Katsyuba, Hüseyin Baris Atakan, Rongrong Xiang

The nematode Caenorhabditis elegans is a suitable model organism in drug screening. Traditionally worms are grown on agar plates, posing many challenges for long-term culture and phenotyping of animals under identical conditions. Microfluidics allows for ' ...

2019

Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans

Johan Auwerx, Martinus Gijs, Matteo Cornaglia, Laurent Mouchiroud, Hüseyin Baris Atakan

The nematode Caenorhabditis elegans is increasingly used as a model for human biology. However, in vivo culturing platforms for C. elegans allowing high-content phenotyping during their life cycle in an automated fashion are lacking so far. Here, a multipl ...

ROYAL SOC CHEMISTRY2019

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Caenorhabditis briggsae

Drug Screening in C. elegans to identify new pharmacological mitochondrial stress inducers

Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos

High-resolution imaging and analysis of the intestinal bacterial load of Caenorhabditis elegans during early adulthood

Microfluidic devices for automated analysis of ingested bacteria in the Caenorhabditis elegans intestine

Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS-1

Deformation-aware Unpaired Image Translation for Pose Estimation on Laboratory Animals

Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans

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Chattez avec Graph Search

Drug Screening in C. elegans to identify new pharmacological mitochondrial stress inducers

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS-1

Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans

Microfluidic devices for automated analysis of ingested bacteria in the Caenorhabditis elegans intestine

High-resolution imaging and analysis of the intestinal bacterial load of Caenorhabditis elegans during early adulthood

Deformation-aware Unpaired Image Translation for Pose Estimation on Laboratory Animals