Concept

Majorité civile

Publications associées (62)

Complement Factor B Polymorphism and the Phenotype of Early Age-related Macular Degeneration

Purpose: Age-related macular degeneration (AMD) has been associated with a number of polymorphisms in genes in the complement pathway. We examined the potential genotype-phenotype correlation of complement factor B (CFB) (R32Q) polymorphisms in Caucasian p ...

Informa Healthcare2014

Reprint of: Musculoskeletal system in the old age and the demand for healthy ageing biomarkers

Martin Kussmann, Sofia Moco, Sebastiano Collino

Population ageing has emerged as a major demographic trend worldwide due to improved health and longevity. This global ageing phenomenon will have a major impact on health-care systems worldwide due to increased morbidity and greater needs for hospitalizat ...

Elsevier Ireland Ltd2014

A Double-differential Actuation for an Assistive Hip Orthosis

Hannes Bleuler, Mohamed Bouri, Jeremy Olivier

The population ageing implies an increasing need for support especially in terms of mobility. Actuated orthoses offer new possibilities to assist walking by compensating the diminished muscular force which occurs with age. In order to assist efficiently th ...

2013

Long-term programming of enhanced aggression by peripuberty stress in female rats

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana

Human literature has linked adverse early life experiences with an increased risk to develop violent behaviors in both boys and girls. We have previously shown that male rats submitted to stress during the peripuberty period display as adults abnormal aggr ...

Elsevier2013

Factors affecting the adoption of vehicle sharing systems by young drivers

Dimitrios Efthymiou

Transportation patterns in big cities are redefined by the growing trend of car ownership and usage costs (e.g. the initial cost of buying a car, the constantly growing fuel prices, additional maintenance and insurance costs and the increased parking deman ...

2013

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Johan Auwerx, Kristina Schoonjans, Carlos Canto Alvarez, Laurent Mouchiroud, Richardus Houtkooper, Dongryeol Ryu, Elena Katsyuba, Norman Lionel Moullan, Adrienne Joëlle Laurence Mottis

NAD(+) is an important cofactor regulating metabolic homeostasis and a rate-limiting substrate for sirtuin deacylases. We show that NAD(+) levels are reduced in aged mice and Caenorhabditis elegans and that decreasing NAD(+) levels results in a further red ...

Cell Press2013

Musculoskeletal system in the old age and the demand for healthy ageing biomarkers

Martin Kussmann, Sofia Moco, Sebastiano Collino

Elsevier Ireland Ltd2013

LRRK2 secretion in exosomes is regulated by 14-3-3

Elpida Tsika, Darren Moore

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset Parkinson's disease (PD). Emerging evidence suggests a role for LRRK2 in the endocytic pathway. Here, we show that LRRK2 is released in extracellular microvesicles (i.e. exosomes) ...

Oxford University Press2013

Combining vernier acuity and visual backward masking as a sensitive test for visual temporal deficits in aging research

Michael Herzog, Maya Roinishvili

Performance in many everyday situations slows down when age increases. The causes of slowing down may be found on any stage of information processing. Here, we show that the combination of a vernier acuity task and the shine-through backward masking paradi ...

Elsevier2011

Genetic Association of Recovery from Eating Disorders: The Role of GABA Receptor SNPs

Pierre Magistretti

Follow-up studies of eating disorders (EDs) suggest outcomes ranging from recovery to chronic illness or death, but predictors of outcome have not been consistently identified. We tested 5151 single-nucleotide polymorphisms (SNPs) in approximately 350 cand ...

2011

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search