Concept
Lacunar stroke
Publications associées (65)
A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data
Stroke, a major global health concern often rooted in cardiac dynamics, demands precise risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2 -VASc \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepa ...
Nature Portfolio2024Influence of DNP Polarizing Agents on Biochemical Processes: TEMPOL in Transient Ischemic Stroke
Mor-Miri Mishkovsky, Jean-Noël Hyacinthe, Mario Gaetano Lepore, Thanh Phong Kevin Lê, Lara Buscemi Estefanell
Hyperpolarization of 13C by dissolution dynamic nuclear polarization (dDNP) boosts the sensitivity of magnetic resonance spectroscopy (MRS), making possible the monitoring in vivo and in real time of the biochemical reactions of exogenously infused 13C-lab ...
2023Preserved Corticospinal Tract Revealed by Acute Perfusion Imaging Relates to Better Outcome After Thrombectomy in Stroke
Friedhelm Christoph Hummel, Philipp Johannes Koch
BACKGROUND:The indication for mechanical thrombectomy (MT) in stroke patients with large vessel occlusion has been constantly expanded over the past years. Despite remarkable treatment effects at the group level in clinical trials, many patients remain sev ...
Philadelphia2023Towards patient-tailored interventions for stroke recovery: graph theoretical approaches and modeling of non-invasive brain stimulation
Stroke is a disease that causes the death of precious brain cells that will never grow back and which will affect one in four humans at some point in their life. While therapies and treatments for this debilitating condition are fairly standard, their outc ...
EPFL2022Early motor skill acquisition in healthy older adults: functional MRI and connectome correlates
decrement have been proposed, such as weakened acquisition of the motor skill. While the processes at play during the initial acquisition phase have been well-characterized in young adults, they were only scarcely investigated in older adults. The goal of ...
EPFL2022Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation
Jean-Marc Vesin, Vincent Schlageter
Purpose: Silent brain infarcts (SBI) are frequently detected in patients with atrial fibrillation (AF), but it is unknown whether SBI are linked to autonomic dysfunction. We aimed to explore the association of autonomic dysfunction with SBI in AF patients. ...
FRONTIERS MEDIA SA2021Detecting Compensatory Motions and Providing Informative Feedback During a Tangible Robot Assisted Game for Post-Stroke Rehabilitation
Pierre Dillenbourg, Friedhelm Christoph Hummel, Barbara Bruno, Maximilian Jonas Wessel, Ayberk Özgür, Hala Khodr
Gamified rehabilitation tackles the problem of keeping patients engaged in, and motivated to do physical rehabilitation to improve its efficacy. However, with respect to standard rehabilitation, patients are freer to move about and may compensate their mot ...
IEEE2021Movement-Related Cortical Potentials in Embodied Virtual Mirror Visual Feedback
Gangadhar Garipelli, Tamara Rossy
Background: Mirror therapy is thought to drive interhemispheric communication, resulting in a balanced activation. We hypothesized that embodied virtual mirror visual feedback (VR-MVF) presented on a computer screen may produce a similar activation. In thi ...
FRONTIERS MEDIA SA2021New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases
Jian Wang, Friedhelm Christoph Hummel
The past decade has brought tremendous progress in diagnostic and therapeutic options for cerebrovascular diseases as exemplified by the advent of thrombectomy in ischemic stroke, benefitting a steeply increasing number of stroke patients and potentially p ...
2021Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls
Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Philip Egger
Background: Noninvasive brain stimulation has been successfully applied to improve stroke impairments in different behavioral domains. Yet, clinical translation is limited by heterogenous comes within and across studies. It has been proposed to develop and ...
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