Concept
Hémorragie digestive
Publications associées (32)
Bioengineering functional organoid models across scales
The last two decades have seen the development of organoid models for many different tissues and organs. Organoids are three-dimensional organ-mimetics derived from stem or progenitor cells comprising various specialized cell types, resembling the architec ...
EPFL2024Bio accessibility of tire-associated organic chemicals in fish gut (Oncorhynchus mykiss): insights from an in vitro digestion model
Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset
Tire and Road Wear Particles (TRWP) account for an important part of the anthropogenic particles released into the environment. There are scientific knowledge gaps as to the potential bio accessibility of chemicals associated with TRWP to aquatic organisms ...
2022In Vitro Digestion of Tire Particles in a Fish Model (Oncorhynchus mykiss): Solubilization Kinetics of Heavy Metals and Effects of Food Coingestion
Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset
Tire and road wear particles (TRWP) have been shown to represent a large part of anthropogenic particles released into the environment. Nevertheless, the potential ecological risk of TRWP in the different environmental compartments and their potential toxi ...
2021Symptom Prediction and Mortality Risk Calculation for COVID-19 Using Machine Learning
Nahal Mansouri, Sahand Jamal Rahi
Background: Early prediction of symptoms and mortality risks for COVID-19 patients would improve healthcare outcomes, allow for the appropriate distribution of healthcare resources, reduce healthcare costs, aid in vaccine prioritization and self-isolation ...
FRONTIERS MEDIA SA2021De novo development of proteolytically resistant therapeutic peptides for oral administration
Christian Heinis, Luciano Andres Abriata, Florence Pojer, Xudong Kong, Vanessa Carle, Jun Moriya
The oral administration of peptide drugs is hampered by their metabolic instability and limited intestinal uptake. Here, we describe a method for the generation of small target-specific peptides (less than 1,600 Da in size) that resist gastrointestinal pro ...
2020Factors influencing safety and efficacy of intravenous iron-carbohydrate nanomedicines: From production to clinical practice
Iron deficiency is an important subclinical disease affecting over one billion people worldwide. A growing body of clinical records supports the use of intravenous iron-carbohydrate complexes for patients where iron replenishment is necessary and oral iron ...
2020Recapitulating macro-scale tissue self-organization through organoid bioprinting
Matthias Lütolf, Moritz Hofer, Mikhail Nikolaev, Jonathan Brassard
A 3D bioprinting approach has been developed to facilitate tissue morphogenesis by directly depositing organoid-forming stem cells in an extracellular matrix, with the ability to generate intestinal epithelia and branched vascular tissue constructs. Biopri ...
NATURE RESEARCH2020