Concept
Urticaire
Publications associées (12)
Peptide macrocycle inhibitor of coagulation factor XII with subnanomolar affinity and high target selectivity
Christian Heinis, Jonas Alfred Karl Wilbs, Simon Jan Middendorp
Factor XII (FXII) is a plasma protease that has emerged in recent years as a potential target to treat or prevent pathological thrombosis, to inhibit contact activation in extracorporeal circulation, and to treat the swelling disorder hereditary angioedema ...
2017Intimate gut interactions: helminths and the microbiota
Changing exposure to intestinal helminths, or alterations in our intestinal microbiome, have been independently proposed to underlie the increasing incidence of chronic inflammatory diseases including allergy, autoimmunity and inflammatory bowel disease (I ...
Inst Biochemistry & Cell Biology2016Cyclosporin analogues
Cyclosporins are a family of hydrophobic cyclic undecapeptides produced by the fungus Tolypocladium niveum. The main metabolite cyclosporin A (CsA, see Scheme, R = R' = H) is the first line drug currently used to prevent rejection of organ transplants. Its ...
EPFL2005Natural anti-FcepsilonRIalpha autoantibodies may interfere with diagnostic tests for autoimmune urticaria
Lucia Baldi Unser, Martin Vogel
IgG autoantibodies against the alpha-chain of the high affinity IgE receptor are claimed to play a pathogenetic role in autoimmune urticaria. The best methods for detection of functional autoantibodies are currently the autologous serum skin test and the b ...
2004