Publications associées à Evolutionary physiology

Systematic Reduction of Genome Scale Metabolic Reconstructions - redGEM

Vassily Hatzimanikatis, Meriç Ataman, Georgios Fengos, Keng Cher Soh, Daniel Federico Hernandez Gardiol

Genome-scale metabolic reconstructions (GEMs) are valuable resources for understanding and redesigning cellular networks as they encapsulate all the known biochemistry of the organisms from genes to proteins to their functions. Complexity of these large me ...

2015

Phenotypic heterogeneity in metabolic traits among single cells of a rare bacterial species in its natural environment quantified with a combination of flow cell sorting and NanoSIMS

Anders Meibom, Stéphane Laurent Escrig, Martin Ackermann

Populations of genetically identical microorganisms residing in the same environment can display marked variability in their phenotypic traits; this phenomenon is termed phenotypic heterogeneity. The relevance of such heterogeneity in natural habitats is u ...

Frontiers Research Foundation2015

Tgfbi/Bigh3 silencing activates ERK in mouse retina

BIGH3 is a secreted protein, part of the extracellular matrix where it interacts with collagen and integrins on the cell surface. BIGH3 can play opposing roles in cancer, acting as either tumor suppressor or promoter, and its mutations lead to different fo ...

Academic Press Ltd- Elsevier Science Ltd2015

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

Didier Trono, Denis Duboule, Marion Leleu, Daniël Noordermeer, Guillaume Andrey

Hox genes are major determinants of the animal body plan, where they organize structures along both the trunk and appendicular axes. During mouse limb development, Hoxd genes are transcribed in two waves: early on, when the arm and forearm are specified, a ...

Amer Assoc Advancement Science2013

Towards kinetic modeling of genome-scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiology constraints

Vassily Hatzimanikatis, Ljubisa Miskovic, Keng Cher Soh, Anirikh Chakrabarti

Mathematical modeling is an essential tool for a comprehensive understanding of cell metabolism and its interactions with the environmental and process conditions. Recent developments in the construction and analysis of stoichiometric models made it possib ...

2013

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

Johan Auwerx, Pénélope Andreux, Evan Graehl Williams, Xu Wang

The gastrointestinal tract harbors a complex and diverse microbiota that has an important role in host metabolism. Microbial diversity is influenced by a combination of environmental and host genetic factors and is associated with several polygenic disease ...

Public Library of Science2012

The dark sides of capillary morphogenesis gene 2

Françoise Gisou van der Goot Grunberg, Julie Deuquet Ariosa

Capillary morphogenesis gene 2 (CMG2) is a type I membrane protein involved in the homeostasis of the extracellular matrix. While it shares interesting similarities with integrins, its exact molecular role is unknown. The interest and knowledge about CMG2 ...

2012

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains

David Lyndon Emsley

Maintaining homeostasis in higher organisms involves a complex interplay of multiple ubiquitous and organ-specific molecular mechanisms that can be characterized using functional genomics technologies such as transcriptomics, proteomics, and metabonomics a ...

AMER CHEMICAL SOC2011

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Evolutionary physiology

Systematic Reduction of Genome Scale Metabolic Reconstructions - redGEM

Phenotypic heterogeneity in metabolic traits among single cells of a rare bacterial species in its natural environment quantified with a combination of flow cell sorting and NanoSIMS

Tgfbi/Bigh3 silencing activates ERK in mouse retina

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

Towards kinetic modeling of genome-scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiology constraints

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

The dark sides of capillary morphogenesis gene 2

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains

Evolutionary plasticity of segmentation clock networks

Network Self-organization explains the distribution of synaptic efficacies in neocortex

Graph Chatbot

Chattez avec Graph Search

The dark sides of capillary morphogenesis gene 2

Tgfbi/Bigh3 silencing activates ERK in mouse retina

Evolutionary plasticity of segmentation clock networks

Network Self-organization explains the distribution of synaptic efficacies in neocortex

Phenotypic heterogeneity in metabolic traits among single cells of a rare bacterial species in its natural environment quantified with a combination of flow cell sorting and NanoSIMS

Towards kinetic modeling of genome-scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiology constraints

Systematic Reduction of Genome Scale Metabolic Reconstructions - redGEM

A switch between topological domains underlies HoxD genes collinearity in mouse limbs

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains