Concept

Uridine diphosphate glucose

Publications associées (43)

Glucose sensitivity through oxidation responsiveness. An example of cascade-responsive nano-sensors

Jeffrey Alan Hubbell, Nicola Tirelli, Annemie Rehor

Oxidn.-sensitive nanoparticles have been decorated with an oxidizing enzyme (glucose oxidase) for release behavior that is responsive to the presence of the enzyme substrate (glucose). [on SciFinder (R)] ...

2005

In vivo measurement of glucose utilization in rats using a beta-microprobe: direct comparison with autoradiography

Pierre Magistretti, Jean-Marie Petit, Christian Morel

A new beta-microprobe (betaP) has been used to locally measure the time-concentration curve of a radiolabeled substance. The betaP, analogous to positron emission tomography methodology, is useful for in vivo animal studies because it can acquire time-conc ...

2004

Dynamic or inert metabolism? Turnover of N-acetyl aspartate and glutathione from D-[1-13C]glucose in the rat brain in vivo

Rolf Gruetter

The rate of (13)C-label incorporation into both aspartyl (NAA C3) and acetyl (NAA C6) groups of N-acetyl aspartate (NAA) was simultaneously measured in the rat brain in vivo for up to 19 h of [1-(13)C]glucose infusion (n = 8). Label incorporation was detec ...

Wiley-Blackwell2004

Lactate is a preferential oxidative energy substrate over glucose for neurons in culture

Pierre Magistretti, Luc Pellerin

The authors investigated concomitant lactate and glucose metabolism in primary neuronal cultures using 13C- and 1H-NMR spectroscopy. Neurons were incubated in a medium containing either [1-13C]glucose and different unlabeled lactate concentrations, or unla ...

2003

In vivo 13C NMR assessment of brain glycogen concentration and turnover in the awake rat

Rolf Gruetter

Brain glycogen metabolism was recently observed in vivo and found to be very slow in the lightly alpha-chloralose anesthetized rat [J. Neurochem. 73 (1999) 1300]. Based on that slow turnover, the total glycogen content in the awake rat brain and its turnov ...

Elsevier2003

Indirect biomass determination in case of non-constant metabolic rates

Urs von Stockar, Ian William Marison, Martin Rhiel

A novel approach for indirect biomass detn. in case of non-const. specific metabolic rates is reported. Specific glucose consumption rate was detd. during a first calibration culture for both free suspended and immobilized cells. It was expressed as a line ...

1999

PPARgamma activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes

Johan Auwerx, Kristina Schoonjans

It is currently thought that the effects of PPARgamma activation on glucose homeostasis may be due to the effect of this nuclear receptor on the production of adipocyte-derived signalling molecules, which affect muscle glucose metabolism. Potential signall ...

Elsevier1998

Localized in vivo 13C-NMR of glutamate metabolism in the human brain: Initial results at 4 Tesla

Rolf Gruetter, Sun Hee Kim

Using optimized administration of 13C-labeled glucose, the time course of the specific activity of glucose was measured directly by in vivo 13C-NMR in the human brain at 4 Tesla. Subsequent label incorporation was measured at the C2, C3 and C4 positions of ...

1998

Peroxisome proliferator-activated receptors, orphans with ligands and functions

Johan Auwerx, Kristina Schoonjans

The three peroxisome proliferator-activated receptors (PPARs), PPAR alpha, delta and gamma, form a subfamily of the nuclear hormone receptor gene family. PPAR alpha has been shown to bind and be activated by leukotriene B4 and fibrates, whereas prostagland ...

1997

Observation of resolved glucose signals in 1H NMR spectra of the human brain at 4 tesla

Rolf Gruetter

Measurement of the resonances of glucose between 3.2 and 3.9 ppm in 1H NMR spectra from the human brain is difficult due to spectral overlap with peaks from more concentrated metabolites. The H1 resonance of α-D-glucose at 5.23 ppm is resolved from other m ...

1996

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