Concept

Optic tract

Publications associées (34)

A viral vector based in vivo model of tauopathy to explore therapeutic strategies against tau pathology

Tauopathies are neurodegenerative diseases whose common pathological feature is the intraneuronal accumulation of tau aggregates. Tau protein has various roles in the neuron, among which stabilization of microtubules (MT), regulation of synaptic activity o ...

EPFL2019

Cortical and thalamic connectivity of occipital visual cortical areas 17, 18, 19, and 21 of the domestic ferret (Mustela putorius furo)

Giorgio Innocenti

The present study describes the ipsilateral and contralateral corticocortical and corticothalamic connectivity of the occipital visual areas 17, 18, 19, and 21 in the ferret using standard anatomical tract-tracing methods. In line with previous studies of ...

2019

Soft Three-dimensional self-opening intraneural peripheral interface for optic nerve stimulation

Diego Ghezzi, Eleonora Borda, Marta Jole Ildelfonsa Airaghi Leccardi

Retinitis Pigmentosa and age-related macular degeneration are two of the principal causes of blindness in industrialized countries, for which there is still no established prevention, treatment or cure. In the past decade, retinal prostheses emerged as pro ...

2018

Parietofrontal motor pathways and their association with motor function after stroke

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Philipp Johannes Koch

Corticocortical interactions between the primary motor cortex, the ventral premotor cortex and posterior parietal motor areas, such as the anterior and caudal intraparietal sulcus, are relevant for skilled voluntary hand function. It remains unclear to wha ...

Oxford University Press2015

A polymer-based interface restores light sensitivity in blind rats

Diego Ghezzi

Purpose: Sight restoration is one of the new frontiers for prosthetic devices that enable the electrical stimulation of neurons. In particular, diseases affecting the retinal pigment epithelium and photoreceptors but preserve the inner retinal layers are p ...

2014

A polymer-based interface restores light sensitivity in blind rats

Diego Ghezzi

Progressive degeneration of photoreceptors is one of the major causes of adult blindness in “industrialized” countries; as an example, Retinitis pigmentosa defines a set of monogenic hereditary retinal diseases, with a prevalence of 1:4000 worldwide, cause ...

2014

Accurate resistivity mouse brain mapping using microelectrode arrays

Philippe Renaud, Vincent Delattre, Patrick Fraering, Amélie Barbara Hildegarde Béduer, Sébastien Mosser, Pierre Joris

Electrical impedance spectroscopy measurements were performed in post-mortem mice brains using a flexible probe with an embedded micrometric electrode array. Combined with a peak resistance frequency method this allowed obtaining intrinsic resistivity valu ...

Elsevier2014

Pupil responses derived from outer and inner retinal photo reception are normal in patients with hereditary optic neuropathy

Mirjam Münch, Lorette Leon

We compared the pupil responses originating from outer versus inner retinal photoreception between patients with isolated hereditary optic neuropathy (HON, n = 8) and healthy controls (n = 8). Three different testing protocols were used. For the first two ...

Academic Press Ltd- Elsevier Science Ltd2014

ALDH1A3 loss of function causes bilateral anophthalmia/microphthalmia and hypoplasia of the optic nerve and optic chiasm

The major active retinoid, all-trans retinoic acid, has long been recognized as critical for the development of several organs, including the eye. Mutations in STRA6, the gene encoding the cellular receptor for vitamin A, in patients with MatthewWood syndr ...

Oxford University Press2013

Intrinsically photosensitive retinal ganglion cells: classification, function and clinical implications

Purpose of review The discovery of a new class of intrinsically photosensitive retinal ganglion cells (ipRGCs) revealed their superior role for various nonvisual biological functions, including the pupil light reflex, and circadian photoentrainment. Recent ...

Lippincott, Williams & Wilkins2013

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