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Complex dynamical networks are ubiquitous in many fields of science from engineering to biology, physics, and sociology. Collective behavior, and in particular synchronization,) is one of the most interesting consequences of interaction of dynamical system ...
The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined system for exploring the link between molecular mechanisms, synaptic circuits, and behavior. The primary somatosensory cortex has an exquisite somatotopic map where ...
How well are single-cell properties reproduced by the present-day neuronal models? Recently, several labs have approached this question by assessing the quality of the models with respect to spike timing prediction or characteristic features of the voltage ...
Whether signals from different sensory modalities converge and interact within primary cortices in humans is unresolved, despite emerging evidence in animals. This is partially because of debates concerning the appropriate analyses of functional magnetic r ...
Human brain oscillatory activity was analysed in the electroencephalographic theta frequency range (4-7 Hz) while subjects executed complex sequential finger movements with varying task difficulty and memory load. Local frontal-midline theta activity was a ...
The prefrontal cortex is specially adapted to generate persistent activity that outlasts stimuli and is resistant to distractors, presumed to be the basis of working memory. The pyramidal network that supports this activity is unknown. Multineuron patch-cl ...
Huntington's disease (HD) pathology is well understood at a histological level but a comprehensive molecular analysis of the effect of the disease in the human brain has not previously been available. To elucidate the molecular phenotype of HD on a genome- ...
Handwriting (HW), unlike reaching or walking, is a high-level motor activity, engaging large parts of cortical and sub-cortical regions that include supplementary motor area(SMA), premotor area(PM), primary motor area(M1), basal ganglia(BG), cerebellum, sp ...
Tactile information is actively acquired and processed in the brain through concerted interactions between movement and sensation. Somatosensory input is often the result of self-generated movement during the active touch of objects, and conversely, sensor ...
To test the hypothesis that somatosensory stimulation would enhance the effects of training functional hand tasks immediately after practice and 1 day later in chronic subcortical stroke patients. ...