Publications de Vincent Jacquemet

Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

Jean-Marc Vesin, Adrian Luca, Vincent Jacquemet

Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...

Oxford Univ Press2016

Influence of atrial substrate on local capture induced by rapid pacing of atrial fibrillation

Jean-Marc Vesin, Vincent Jacquemet, Alexandru Rusu

Preliminary studies showed that the septum area was the only location allowing local capture of both the atria during rapid pacing of atrial fibrillation (AF) from a single site. The present model-based study investigated the influence of atrial substrate ...

Oxford University Press2014

Estimating the time scale and anatomical location of atrial fibrillation spontaneous termination in a biophysical model

Jean-Marc Vesin, Vincent Jacquemet, Laurent Renaud Uldry, Lukas Kappenberger

Due to their transient nature, spontaneous terminations of atrial fibrillation (AF) are difficult to investigate. Apparently, confounding experimental findings about the time scale of this phenomenon have been reported, with values ranging from 1 s to 1 mi ...

Springer-Verlag2012

Optimizing Local Capture of Atrial Fibrillation by Rapid Pacing: Study of the Influence of Tissue Dynamics

Jean-Marc Vesin, Vincent Jacquemet, Laurent Renaud Uldry, Lukas Kappenberger

While successful termination by pacing of organized atrial tachycardias has been observed in patients, rapid pacing of AF can induce a local capture of the atrial tissue but in general no termination. The purpose of this study was to perform a systematic e ...

Springer Verlag2010

Adaptive Multiple Frequency Tracking Algorithm: Detection of Stable Atrial Fibrillation Sources from Standard 12-Lead ECG

Jean-Marc Vesin, Mathieu Lemay, Cédric Duchene, Vincent Jacquemet

The detection of stable atrial fibrillation (AF) sources remains one of the major challenges in the AF management. In this study, we investigated the feasibility of detecting stable AF sources from (non invasive) data simulated by means of numerical proced ...

2009

The Role of Atrial Modeling in the Development of ECG Processing Tools

Jean-Marc Vesin, Mathieu Lemay, Cédric Duchene, Laurent Renaud Uldry, Vincent Jacquemet, Lukas Kappenberger

The standard ECG remains the most common non-invasive tool for assessing atrial fibrillation. Specific signal processing techniques have been developed to improve the diagnosis. However, validation of such tools is challenging and comprehensive invasive da ...

2009

The effect of tissue geometry on the activation recovery interval of atrial myocytes

Vincent Jacquemet

The propagation of electric activity inside a realistically-shaped, thick-walled model of the atria was studied. The membrane kinetics was based on the formulations of Courtemanche, Ramirez and Nattel. In spite of the assumed uniformity of all kinetics par ...

2009

Spontaneous termination of atrial fibrillation: study of the effect of atrial geometry in a biophysical model

Jean-Marc Vesin, Vincent Jacquemet, Laurent Renaud Uldry, Lukas Kappenberger

We studied the mechanisms of spontaneous termination of atrial fibrillation in a biophysical model of human atria, during the eight seconds preceding termination. The earliest detectable changes in the cycle length and the number of wavefronts occurred abo ...

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Dominant Rotors in Atrial Fibrillation identified by means of Spectral Analysis

Vincent Jacquemet

Blackwell Publishing2009

Activity Level of an Atrial Ectopic Focus Observed Through the Equivalent Dipole: a Biophysical Model

Jean-Marc Vesin, Vincent Jacquemet, Mathieu Lemay, Cédric Duchene

Quantifying the role of atrial ectopic foci in the initiation and the maintenance of atrial fibrillation (AF) is a relevant clinical problem. This study aims at assessing the relation between the activity level of an ectopic focus and the complexity of the ...

2009