Philipp Bucher

Cette personne n’est plus à l’EPFL

Publications associées (158)

À propos
Confidentialité
Mentions légales

Page 2 sur 16

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Lukas Kühn, Giovanna Ambrosini, Barbara Grisoni-Neupert, Philipp Bucher, Ramona Pauchard-Batschulat, Otto Hagenbüchle

Regulation of mRNA stability by RNA-protein interactions contributes significantly to quantitative aspects of gene expression. We have identified potential mRNA targets of the AU-rich element binding protein AUF1. Myc-tagged AUF1 p42 was induced in mouse N ...

PUBLIC LIBRARY SCIENCE2018

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

Giovanna Ambrosini, Philipp Bucher, Romain Fernand Pietro Groux

Transcription factors (TFs) regulate gene expression by binding to specific short DNA sequences of 5 to 20-bp to regulate the rate of transcription of genetic information from DNA to messenger RNA. We present PWMScan, a fast web-based tool to scan server-r ...

2018

Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data

Philipp Bucher, Alexandre Coudray

To detect functional somatic mutations in tumor samples, whole-exome sequencing (WES) is often used for its reliability and relative low cost. RNA-seq, while generally used to measure gene expression, can potentially also be used for identification of soma ...

2018

, , , ,

Oxford University Press2018

Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data

Philipp Bucher, Alexandre Coudray

2018

SNP2TFBS-a database of regulatory SNPs affecting predicted transcription factor binding site affinity

Giovanna Ambrosini, Philipp Bucher, Sanjeev Kumar

NATURE PUBLISHING GROUP2018

, ,

NATURE PUBLISHING GROUP2018

SMiLE-seq identifies binding motifs of single and dimeric transcription factors

Didier Trono, Bart Deplancke, Giovanna Ambrosini, Philipp Bucher, Riccardo Dainese, Daniel Alpern, Michaël Imbeault, Romain Fernand Pietro Groux, Alina Isakova, Pernille Yde Rainer

Resolving the DNA-binding specificities of transcription factors (TFs) is of critical value for understanding gene regulation. Here, we present a novel, semiautomated protein-DNA interaction characterization technology, selective microfluidics-based ligand ...

Nature Publishing Group2017

, , , ,

We present an update of the Eukaryotic Promoter Database EPD (http://epd.vital-it.ch), more specifically on the EPDnew division, which contains comprehensive organisms-specific transcription start site (TSS) collections automatically derived from next gene ...

2017

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

Olivier Martin, Vassily Hatzimanikatis, Jacques Rougemont, Giovanna Ambrosini, Nicolas Jean Philippe Guex, Marion Leleu, Nadine Fournier, Krisztian Homicsko, Julien Dorier, Christian Iseli, Fabrice David, Maxime Jan, Sophie Barret, Philipp Bucher, Mauro Delorenzi, Julien Racle, David Gfeller, João Pedro de Matos Rodrigues, Thomas Junier, Niklaus Johner, René Dreos, Rouayda Cavin Perier, Omid Shahmirzadi, Romain Fernand Pietro Groux, Ray Marcel Marin Florez, Somi Reddy Majjigapu, Christophe Bovigny, Marco Pagni, Julien Delafontaine, Sunil Kumar, Delphine Yvette L Grun, Philippe Jacquet, Philippe Moret, Haleh Yasrebi, Daniel Federico Hernandez Gardiol, Samuel Neuenschwander, Heinz Stockinger, Sebastian Schmidt, Lucila Aimo, Yoann Mouscaz, Sara Benmohammed, Thierry Lombardot, Patrick Roelli, Benjamin Paccaud, Linda Dib, Ioannis Xenarios, Olivier Michielin, Amos Bairoch, Thierry Sengstag, Andreas Schmid, Frederic Burdet, Aline Dousse, Madeleine Suffiotti, Nicolas Salamin, Grégoire Rossier, Daniel Schmocker, Atul Sethi, Guillaume Keller, Felipe Aristides Simao Neto, Ni Ai, Leonore Wigger, Marie Ghraichy, Saumya Gupta, Rounak Vyas, Thomas Stricker

The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to t ...

Oxford University Press2016