Daniel Sage

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Publications associées (72)

DeepImageJ: A user-friendly environment to run deep learning models in ImageJ

Michaël Unser, Daniel Sage, Laurène Donati

DeepImageJ offers a user-friendly solution in ImageJ to run trained deep learning models for biomedical image analysis. It includes guiding tools for reliable analyses, contributing to the democratization of deep learning in microscopy. ...

NATURE PORTFOLIO2021

In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

Daniel Sage

Circadian clocks operative in pancreatic islets participate in the regulation of insulin secretion in humans and, if compromised, in the development of type 2 diabetes (T2D) in rodents. Here we demonstrate that human islet alpha- and beta-cells that bear a ...

National Academy of Sciences2020

W2S: Microscopy Data with Joint Denoising and Super-Resolution for Widefield to SIM Mapping

Sabine Süsstrunk, Daniel Sage, Thierry Laroche, Arne Seitz, Majed El Helou, Ruofan Zhou

In fluorescence microscopy live-cell imaging, there is a critical trade-off between the signal-to-noise ratio and spatial resolution on one side, and the integrity of the biological sample on the other side. To obtain clean high-resolution (HR) images, one ...

2020

Achieving high-resolution thermal imagery in low-contrast lake surface waters by aerial remote sensing and image registration

David Andrew Barry, Ulrich Lemmin, Daniel Sage, Abolfazl Irani Rahaghi

A two-platform measurement system for realizing airborne thermography of the Lake Surface Water Temperature (LSWT) with ~0.8 m pixel resolution (sub-pixel satellite scale) is presented. It consists of a tethered Balloon Launched Imaging and Monitoring Plat ...

2019

Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

Michaël Unser, Daniel Sage, Thanh-An Michel Pham, Tomas Lukes, Seamus John Holden, Anna Archetti, Thomas Pengo, Ricardo Henriques, Silvia Colabrese, Anurag Agrawal

With the widespread uptake of two-dimensional (2D) and three-dimensional (3D) single-molecule localization microscopy (SMLM), a large set of different data analysis packages have been developed to generate super-resolution images. In a large community effo ...

2019

Deforming Tessellations for the Segmentation of Cell Aggregates

Michaël Unser, Daniel Sage, Anaïs Laure Marie-Thérèse Badoual, Aymeric Alexandre Galan

We present a new active contour to segment cell aggregates. We describe it by a smooth tessellation that is attracted toward the cell membranes. Our approach relies on subdivision schemes that are tightly linked to the theory of wavelets. The shape is enco ...

IEEE2019

Closed-Form Expression of the Fourier Ring-Correlation for Single-Molecule Localization Microscopy

Michaël Unser, Daniel Sage, Thanh-An Michel Pham, Emmanuel Emilien Louis Soubies

Single-molecule localization microscopy (SMLM) is a popular microscopic technique that achieves super resolution imaging by localizing individual blinking molecules in thousands of frames. Therefore, the reconstructed high-resolution image is a combination ...

IEEE2019

Pocket guide to solve inverse problems with GlobalBioIm

Michaël Unser, Daniel Sage, Thanh-An Michel Pham, Laurène Donati, Emmanuel Emilien Louis Soubies, Ferréol Arnaud Marie Soulez, Michael Thompson McCann, Thomas Jean Debarre

GlobalBioIm is an open-source MATLAB (R) library for solving inverse problems. The library capitalizes on the strong commonalities between forward models to standardize the resolution of a wide range of imaging inverse problems. Endowed with an operator-al ...

2019

Parametric Experimental Study and Design of Experiment Modelling of Sapphire Grinding

Daniel Sage

This study investigates and models the grinding process of single crystal sapphire. Five parameters: the wheel speed, the feed speed, the vertical feed, the ultrasonic assistance and the crystallographic direction were considered via a design of experiment ...

Elsevier2017

Investigating Focal Adhesion Substructures by Localization Microscopy

Aleksandra Radenovic, Daniel Sage, Lely Feletti, Hendrik Georges Deschout

Cells rely on focal adhesions (FAs) to carry out a variety of important tasks, including motion, environmental sensing, and adhesion to the extracellular matrix. Although attaining a fundamental characterization of FAs is a compelling goal, their extensive ...

Elsevier2017

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In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

Daniel Sage

National Academy of Sciences2020

Achieving high-resolution thermal imagery in low-contrast lake surface waters by aerial remote sensing and image registration

David Andrew Barry, Ulrich Lemmin, Daniel Sage, Abolfazl Irani Rahaghi

2019