Publications de Alke Fink | EPFL Graph Search

The need for awareness and action in managing nanowaste

Waste containing nanomaterials — or nanowaste — is an emerging safety concern worldwide, warranting specific environmentally sound waste management and regulation. ...

2023

NanoSafe III: A User Friendly Safety Management System for Nanomaterials in Laboratories and Small Facilities

Thierry Meyer, Anna Maria Novello, Alke Fink, Elina Buitrago

Research in nanoscience continues to bring forward a steady stream of new nanomaterials and processes that are being developed and marketed. While scientific committees and expert groups deal with the harmonization of terminology and legal challenges, risk ...

2021

An Atomistic Look into Bio-inspired Nanoparticles and their Molecular Interactions with Cells

Francesco Stellacci, Alke Fink, Pablo Campomanes Ramos, Stefano Vanni

Nanoparticles (NPs) have sizes that approach those of pathogens and they can interact with the membranes of eukaryotic cells in an analogous fashion. Typically, NPs are taken up by the cell via the plasma membrane by receptor-mediated processes and subsequ ...

SWISS CHEMICAL SOC2019

Recent advances in nano-bio-interactions: Editorial

Paul Bowen, Sami Rtimi, Alke Fink

ELSEVIER SCIENCE BV2019

Cellulose Nanocrystals with Tethered Polymer Chains: Chemically Patchy versus Uniform Decoration

Harm-Anton Klok, Alke Fink, Justin Orazio Zoppe, Théo Gaston Gérard Lachat, Alix Vaimiti Marie Dupire

The site-specific surface modification of colloidal substrates, yielding "patchy" nanoparticles, is a rapidly expanding area of research as a result of the new complex structural hierarchies that are becoming accessible to chemists and materials scientists ...

2017

Engineered nanomaterials: toward effective safety management in research laboratories

Heinrich Hofmann, Thierry Meyer, Amela Groso, Alke Fink

Background: It is still unknown which types of nanomaterials and associated doses represent an actual danger to humans and environment. Meanwhile, there is consensus on applying the precautionary principle to these novel materials until more information is ...

BioMed Central2016

MULTIFUNCTIONALIZED SPIONs FOR NUCLEAR TARGETING: CELL UPTAKE AND GENE EXPRESSION

Heinrich Hofmann, Alke Fink, Jatuporn Salaklang

Superparamagnetic iron oxide nanoparticles (SPIONs) are used in many biological applications, which necessitate intracellular targeting. Here, we investigate intracellular localization and gene expression in HeLa cells after treatment with functionalized S ...

World Scientific Publ Co Pte Ltd2014

Spatial SPION Localization in Liposome Membranes

Davide Demurtas, Alke Fink

Nanocarriers, including liposomes, offer great opportunities for targeted and controlled therapy. The development in this field has led to a large panel of drug delivery systems, which can be classified into 3 different nanovector generations. However, the ...

Institute of Electrical and Electronics Engineers2013

Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro

Alke Fink, Marc Moniatte

It is known that the nanoparticle-cell interaction strongly depends on the physicochemical properties of the investigated particles. In addition, medium density and viscosity influence the colloidal behaviour of nanoparticles. Here, we show how nanoparticl ...

Royal Soc Chemistry2013

Improved dynamic response assessment for intra-articular injected iron oxide nanoparticles

Heinrich Hofmann, Alke Fink, Jatuporn Salaklang

The emerging importance of nanoparticle technology, including iron oxide nanoparticles for monitoring development, progression, and treatment of inflammatory diseases such as arthritis, drives development of imaging techniques. Studies require an imaging p ...

Wiley-Blackwell2012