Martin Villiger

Cette personne n’est plus à l’EPFL

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Publications associées (18)

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Theo Lasser, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley, Michael Friedrich

Aims/hypothesis Structural and functional imaging of the islets of Langerhans and the insulin-secreting beta cells represents a significant challenge and a long-lasting objective in diabetes research. In vivo microscopy offers a valuable insight into beta ...

Springer Verlag2009

Optical apparatus for dual beam heterodyne Fourier domain optical coherence tomography, has detector that synchronizes phase shift such that sample signal or sample interface moving at arbitrary velocity is detected by phase change

Theo Lasser, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

NOVELTY - The apparatus has an optical unit for splitting a source field to produce and combine reference and biomedical sample light fields. An optical and electronic unit records a spectral interference pattern between combined light fields. A controlled ...

2008

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

Resonant Doppler Fourier Domain Optical Coherence Tomography is a functional imaging modality for quantifying fast tissue flow. The method profits from the effect of interference fringe blurring in spectrometer-based FDOCT in the presence of sample motion. ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2007

Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

Resonant Doppler Fourier domain optical coherence tomography (FDOCT) is a functional imaging tool for extracting tissue flow. The method is based on the effect of interference fringe blurring in spectrometer-based FDOCT, where the path difference between s ...

SPIE Society of Photo-optical Instrumentation Engineers2007

Resonant Doppler flow imaging and optical vivisection of retinal blood vessels

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann

For Fourier domain optical coherence tomography any sample movement during camera integration causes blurring of interference fringes and as such reduction of sensitivity for flow detection. The proposed method overcomes this problem by phase-matching a re ...

2007

Vectorial retinal blood flow and optical vessel vivisection for 3D angiography with high resolution resonant Doppler OCT

Theo Lasser, Martin Villiger, Rainer Leitgeb, Cédric Blatter, Adrian Bachmann, Roland Michaely

PURPOSE: To perform high speed and completely non-invasive 3D angiography at the optic nerve head region and to reconstruct vectorial 3D blood flow from optically segmented blood vessel structure as a pre-requisite for testing retinal function and physiolo ...

2007

Optical imaging apparatus for sample imaging method e.g. in-vivo measurement of full three-dimensional tissue volume has at least one detector that detects resulting spectral interference pattern at exit of interferometer

Theo Lasser, Martin Villiger, Rainer Leitgeb, Adrian Bachmann, Lukas Steinmann

The invention concerns an optical imaging apparatus comprising (o) a light source (1) , (p) sample holding means, (q) an interferometer, (r) reference means, (s) an objective (8) which is adapted to have its sample side focal plane crossing a sample held i ...

2007

Extended focus depth for Fourier domain optical coherence microscopy

Theo Lasser, Martin Villiger, Rainer Leitgeb, Lukas Steinmann, Adrian Bachmann

We report on a new detection scheme for Fourier domain optical coherence microscopy that exhibits high transverse resolution along an axially extended focal range. Nearly constant transverse resolution of ∼1.5 μm along a focal range of 200 μm is experiment ...

2006

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Optical apparatus for dual beam heterodyne Fourier domain optical coherence tomography, has detector that synchronizes phase shift such that sample signal or sample interface moving at arbitrary velocity is detected by phase change

Theo Lasser, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

2008

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Theo Lasser, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley, Michael Friedrich

Springer Verlag2009

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2007

Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

Theo Lasser, Cédric Blatter, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Roland Michaely

SPIE Society of Photo-optical Instrumentation Engineers2007

Optical imaging apparatus for sample imaging method e.g. in-vivo measurement of full three-dimensional tissue volume has at least one detector that detects resulting spectral interference pattern at exit of interferometer

Theo Lasser, Martin Villiger, Rainer Leitgeb, Adrian Bachmann, Lukas Steinmann

2007