Publications de Michael Friedrich

Novel micropatterns mechanically control fibrotic reactions at the surface of silicone implants

Dominique Pioletti, Hicham Majd, Michael Friedrich, Boris Hinz, Silvio Ramondetti, Giorgio Pietramaggiori

Over the past decade, various implantable devices have been developed to treat diseases that were previously difficult to manage such diabetes, chronic pain, and neurodegenerative disorders. However, translation of these novel technologies into clinical pr ...

Elsevier2015

Functional optical coherent imaging platform for medical application e.g. neurosurgery, has active camera unit that captures image of specific region of test subject after transmitting stimulus signals

Dimitri Nestor Alice Van De Ville, Theo Lasser, Michael Friedrich, Marcel Leutenegger, Martin Villiger, Iwan Märki, Erica Martin-Williams

The present invention relates to a functional optical coherent imaging (fOCI) platform comprising at least one active camera unit (ACU) comprising a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected ...

2010

In vivo imaging of pancreatic endocrine islets

Theo Lasser, Christophe Pache, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Extended focus optical coherence microscope (xfOCM) circumvents the compromise between lateral resolution and depth of field by us of a Bessel-like illumination beam. The high sensitivity and parallel depth profiling of Fourier domain optical coherence tom ...

SPIE2009

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Aims/hypothesis Structural and functional imaging of the islets of Langerhans and the insulin-secreting beta cells represents a significant challenge and a long-lasting objective in diabetes research. In vivo microscopy offers a valuable insight into beta ...

Springer Verlag2009

In Vivo extended focus Optical Coherence Microscopy of endocrine islets of Langerhans in mice

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Rapid acquisition of volumetric data is a mandatory prerequisite for small animal in vivo imaging. Due to its high sensitivity and capacity to extract the sample depth profile in parallel Fourier Domain Optical Coherence Tomography (FDOCT) complies with th ...

2009

Object i.e. aneurysm, examining method for brain of patient, involves evaluating sequence of images by associating pixels with analysis image value depending on temporal changes of image values of pixels in specified frequency range

Theo Lasser, Michael Friedrich, Marcel Leutenegger, Antonio Lopez, Erica Martin-Williams

NOVELTY - The method involves illuminating an object i.e. aneurysm, with measuring light with wavelengths ranging from 790 nanometer to 820 nanometer, and recording a sequence of images (21, 22) i.e. white light image, of the illuminated object. The sequen ...

2009

Towards in vivo small animal imaging

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel and allows very high volume acquisition rates. An illumin ...

2008

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