Henry Markram

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Publications associées (169)

Simplification of spiking neural network models

Wulfram Gerstner, Henry Markram, Eilif Benjamin Muller, James Gonzalo King, Idan Segev, Christian Antonio Pozzorini, Willem Anna Mark Wybo, Christian Andreas Rössert, Csaba Erö

The simplification of neural network models is described. For example, a method for simplifying a neural network model includes providing the neural network model to be simplified, defining a first temporal filter for the conveyance of input from a neuron ...

2024

Cell density quantification of high resolution Nissl images of the juvenile rat brain

Henry Markram, Olivier Burri, Rodrigo de Campos Perin, Ying Shi, Julie Meystre, Daniel Keller

Copyright © 2024 Meystre, Jacquemier, Burri, Zsolnai, Frank, Vieira, Shi, Perin, Keller and Markram.Nissl histology underpins our understanding of brain anatomy and architecture. Despite its importance, no high-resolution datasets are currently available i ...

2024

BlueCelluLab: Biologically Detailed Neural Network Experimentation API

Henry Markram, Eilif Benjamin Muller, Lida Kanari, Mustafa Anil Tuncel, Werner Alfons Hilda Van Geit, Darshan Mandge, Aurélien Tristan Jaquier

The NEURON simulator, established in 1984 and continuously developed since, stands as the preeminent tool for neuron simulation within computational neuroscience. Its widespread adoption and compatibility with computational clusters and supercomputers unde ...

The Open Journal2024

Brain Metabolism in Health and Neurodegeneration: The Interplay Among Neurons and Astrocytes

Henry Markram, Daniel Keller, Jay Coggan, Polina Shichkova

The regulation of energy in the brain has garnered substantial attention in recent years due to its significant implications in various disorders and aging. The brain’s energy metabolism is a dynamic and tightly regulated network that balances energy deman ...

MDPI AG2024

Ultraliser: a framework for creating multiscale, high-fidelity and geometrically realistic 3D models for in silico neuroscience

Pierre Magistretti, Henry Markram, Felix Schürmann, Daniel Keller, Marwan Muhammad Ahmed Abdellah, Jay Coggan, Nadir Roman Guerrero, Juan José García Cantero, Alessandro Enrico Foni, Eleftherios Zisis

Ultraliser is a neuroscience-specific software framework capable of creating accurate and biologically realistic 3D models of complex neuroscientific structures at intracellular (e.g. mitochondria and endoplasmic reticula), cellular (e.g. neurons and glia) ...

2023

A universal workflow for creation, validation and generalization of detailed neuronal models

Henry Markram, Srikanth Ramaswamy, Mustafa Anil Tuncel, Werner Alfons Hilda Van Geit, Alexis Arnaudon, Christian Andreas Rössert, Maria Reva, Tanguy Pierre Louis Damart, Darshan Mandge

Detailed single neuron modeling is widely used to study neuronal functions. While cellular and functional diversity across the mammalian cortex is vast, most of the available computational tools are dedicated to the reproduction of a small set of specific ...

Cambridge2023

Simulating Temporal Interference Stimulation

Henry Markram, Michael Reimann, Felix Schürmann

SPRINGER2023

Thalamic control of sensory processing and spindles in a biophysical somatosensory thalamoreticular circuit model of wakefulness and sleep

Henry Markram, Sean Lewis Hill, Michael Reimann, Rodrigo de Campos Perin, James Gonzalo King, Ying Shi, Rajnish Ranjan, Mustafa Anil Tuncel, Samuel Claude Kerrien, Polina Litvak

2023

Controlling morpho-electrophysiological variability of neurons with detailed models

Henry Markram, Lida Kanari, Werner Alfons Hilda Van Geit, Alexis Arnaudon, Maria Reva, Mickael Maurice Zbili

Variability, which is known to be a universal feature among biological units such as neuronal cells, holds significant importance, as, for example, it enables a robust encoding of a high volume of information in neuronal circuits and prevents hypersynchron ...

Cell Press2023

Blue Brain Nexus: An open, secure, scalable system for knowledge graph management and data-driven science

Henry Markram, Sean Lewis Hill, Samuel Claude Kerrien, Carolina Johanna Elisabeth Lindqvist, Alejandra Garcia Rojas Martinez, Huanxiang Lu, Mohameth François Sy, Anna-Kristin Kaufmann, Jonathan Raël Lurie, Henry Genet

Modern data-driven science often consists of iterative cycles of data discovery, acquisition, preparation, analysis, model building and validation leading to knowledge discovery as well as dissemination at scale. The unique challenges of building and simul ...

2023

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Ultraliser: a framework for creating multiscale, high-fidelity and geometrically realistic 3D models for in silico neuroscience

2023

A universal workflow for creation, validation and generalization of detailed neuronal models

Henry Markram, Srikanth Ramaswamy, Mustafa Anil Tuncel, Werner Alfons Hilda Van Geit, Alexis Arnaudon, Christian Andreas Rössert, Maria Reva, Tanguy Pierre Louis Damart, Darshan Mandge

Cambridge2023

Thalamic control of sensory processing and spindles in a biophysical somatosensory thalamoreticular circuit model of wakefulness and sleep

Henry Markram, Sean Lewis Hill, Michael Reimann, Rodrigo de Campos Perin, James Gonzalo King, Ying Shi, Rajnish Ranjan, Mustafa Anil Tuncel, Samuel Claude Kerrien, Polina Litvak

2023