Mauro Delorenzi

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Publications associées (38)

Selecting control genes for RT-QPCR using public microarray data

Darlene Goldstein, Mauro Delorenzi, Vlad Popovici

Background: Gene expression analysis has emerged as a major biological research area, with real-time quantitative reverse transcription PCR (RT-QPCR) being one of the most accurate and widely used techniques for expression profiling of selected genes. In o ...

2009

Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'

Mauro Delorenzi

BACKGROUND: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cross-species studies, in particular, have the power of identifying conserved, f ...

BioMed Central2008

Comprehensive spatiotemporal transcriptomic analyses of the ganglionic eminences demonstrate the uniqueness of its caudal subdivision

Mauro Delorenzi, Didier Surdez, Susan Willi Monnerat

The elucidation of mechanisms underlying telencephalic neural development has been limited by the lack of knowledge regarding the molecular and cellular aspects of the ganglionic eminence (GE), an embryonic structure that supplies the brain with diverse se ...

Elsevier2008

Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

Darlene Goldstein, Mauro Delorenzi, Thierry Sengstag, Benjamin Haibe-Kains

Introduction Breast cancer subtyping and prognosis have been studied extensively by gene expression profiling, resulting in disparate signatures with little overlap in their constituent genes. Although a previous study demonstrated a prognostic concordance ...

2008

Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler

Mauro Delorenzi

2008

Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood

Mauro Delorenzi, Heike Runne

Highly quantitative biomarkers of neurodegenerative disease remain an important need in the urgent quest for disease-modifying therapies. For Huntington's disease (HD), a genetic test is available (trait marker), but necessary state markers are still in de ...

National Academy of Sciences2007

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

Darlene Goldstein, Mauro Delorenzi, Thierry Sengstag

To test the hypotheses that mutant huntingtin protein length and wild-type huntingtin dosage have important effects on disease-related transcriptional dysfunction, we compared the changes in mRNA in seven genetic mouse models of Huntington's disease (HD) a ...

Oxford University Press2007

Regional and cellular gene expression changes in human Huntington's disease brain

Darlene Goldstein, Mauro Delorenzi, Doris Chau Voo Thu, Thierry Sengstag

Huntington's disease (HD) pathology is well understood at a histological level but a comprehensive molecular analysis of the effect of the disease in the human brain has not previously been available. To elucidate the molecular phenotype of HD on a genome- ...

Oxford University Press2006

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Selecting control genes for RT-QPCR using public microarray data

Darlene Goldstein, Mauro Delorenzi, Vlad Popovici

2009

Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'

Mauro Delorenzi

BioMed Central2008

Comprehensive spatiotemporal transcriptomic analyses of the ganglionic eminences demonstrate the uniqueness of its caudal subdivision

Mauro Delorenzi, Didier Surdez, Susan Willi Monnerat

Elsevier2008

Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

Darlene Goldstein, Mauro Delorenzi, Thierry Sengstag, Benjamin Haibe-Kains

2008

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

Darlene Goldstein, Mauro Delorenzi, Thierry Sengstag

Oxford University Press2007