Publications de Wietske Van der Zwaag

Whole-body somatotopic maps in the cerebellum revealed with 7T fMRI

The cerebellum is known to contain a double somatotopic body representation. While the anterior lobe body map has shown a robust somatotopic organization in previous fMRI studies, the representations in the posterior lobe have been more difficult to observ ...

2020

Metabolite concentration changes associated with positive and negative BOLD responses in the human visual cortex: A functional MRS study at 7 Tesla

Rolf Gruetter, Yohan Boillat, Lijing Xin, Wietske Van der Zwaag

Negative blood oxygenation-level dependent (BOLD) signal observed during task execution in functional magnetic resonance imaging (fMRI) can be caused by different mechanisms, such as a blood-stealing effect or neuronal deactivation. Electrophysiological re ...

2019

Whole brain measurements of the positive BOLD response variability during a finger tapping task at 7 T show regional differences in its profiles

Wietske Van der Zwaag, Yohan Boillat

PURPOSE: The positive BOLD response can vary across brain regions. Here, the positive BOLD responses of motor regions, including the cerebellum, were investigated by fast fMRI acquisition. METHODS: The participants were asked to perform an event-related fi ...

Wiley2019

Chronotopic maps in human supplementary motor area

Wietske Van der Zwaag, Domenica Bueti

Time is a fundamental dimension of everyday experiences. We can unmistakably sense its passage and adjust our behavior accordingly. Despite its ubiquity, the neuronal mechanisms underlying the capacity to perceive time remains unclear. Here, in two experim ...

2019

Cortical laminar assessment of T1 and T2*in the cerebellum of MS patients and controls at 7T MRI

Wietske Van der Zwaag, Cristina Granziera, Yohan Boillat

WILEY2019

Cerebellar cortical laminar analysis of T1 relaxation times at 7T MRI shows widespread cerebellar cortex damage in early relapsing-remitting MS patients but no correlation with clinical deficits

Wietske Van der Zwaag, Yohan Boillat, Cristina Granziera, Kieran O'Brien

SAGE PUBLICATIONS LTD2019

Surface-based characteristics of the cerebellar cortex visualized with ultra-high field MRI

Wietske Van der Zwaag, Gunnar Krüger, Cristina Granziera, Guillaume Bonnier, Kieran O'Brien, Yohan Boillat, Mario Joao Fartaria de Oliveira

Although having a relatively homogeneous cytoarchitectonic organization, the cerebellar cortex is a heterogeneous region characterized by different amounts of myelin, iron and protein expression profiles. In this study, we used quantitative T1 and T2* mapp ...

2018

Representations of time in human frontoparietal cortex

Wietske Van der Zwaag, Domenica Bueti

Precise time estimation is crucial in perception, action and social interaction. Previous neuroimaging studies in humans indicate that perceptual timing tasks involve multiple brain regions; however, whether the representation of time is localized or distr ...

2018

Mapping and characterization of positive and negative BOLD responses to visual stimulation in multiple brain regions at 7T

Rolf Gruetter, Wietske Van der Zwaag, João Pedro Forjaco Jorge, Patricia Figueiredo

External stimuli and tasks often elicit negative BOLD responses in various brain regions, and growing experimental evidence supports that these phenomena are functionally meaningful. In this work, the high sensitivity available at 7T was explored to map an ...

Wiley2018

High spatio-temporal resolution in functional MRI with 3D echo planar imaging using cylindrical excitation and a CAIPIRINHA undersampling pattern

Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, Daniel Gallichan, Mayur Narsude, Olivier Benoit Thomas Reynaud

The combination of 3D echo planar imaging (3D-EPI) with a 2D-CAIPIRINHA undersampling scheme provides high flexibility in the optimization for spatial or temporal resolution. This flexibility can be increased further with the addition of a cylindrical exci ...

Wiley2018