Publications de Gunnar Krüger

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, José Pedro Rebelo Ferreira Marques, Gunnar Krüger

Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

WILEY2019

Surface-based characteristics of the cerebellar cortex visualized with ultra-high field MRI

Wietske Van der Zwaag, Gunnar Krüger, Cristina Granziera, Guillaume Bonnier, Kieran O'Brien, Yohan Boillat, Mario Joao Fartaria de Oliveira

Although having a relatively homogeneous cytoarchitectonic organization, the cerebellar cortex is a heterogeneous region characterized by different amounts of myelin, iron and protein expression profiles. In this study, we used quantitative T1 and T2* mapp ...

2018

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE

Meritxell Bach Cuadra, Tobias Kober, Gunnar Krüger, Cristina Granziera, Alexis Roche, Kieran O'Brien, Guillaume Bonnier, Mario Joao Fartaria de Oliveira, Pavel Falkovskiy

Objectives: The aim of this study was to study focal cerebellar pathology in early stages of multiple sclerosis (MS) using ultra-high-field magnetization-prepared 2 inversion-contrast rapid gradient-echo (7T MP2RAGE). Materials and Methods: Twenty early-st ...

Lippincott, Williams & Wilkins2017

Prospective head motion correction using FID-guided on-demand image navigators

Rolf Gruetter, Tobias Kober, Gunnar Krüger, Tom Hilbert, Bénédicte Marie Maréchal, Pavel Falkovskiy, Reto Meuli, Maryna Volodimirivna Waszak, Guillaume Bonnier

PURPOSE: We suggest a motion correction concept that employs free-induction-decay (FID) navigator signals to continuously monitor motion and to guide the acquisition of image navigators for prospective motion correction following motion detection. METHODS: ...

Wiley-Blackwell2017

Accuracy and Precision of Head Motion Information in Multi-Channel Free Induction Decay Navigators for Magnetic Resonance Imaging

Tobias Kober, Gunnar Krüger, Michael Herbst, Maryna Volodimirivna Waszak

Free induction decay (FID) navigators were found to qualitatively detect rigid-body head movements, yet it is unknown to what extent they can provide quantitative motion estimates. Here, we acquired FID navigators at different sampling rates and simultaneo ...

Ieee-Inst Electrical Electronics Engineers Inc2015

An evaluation of volume-based morphometry for prediction of mild cognitive impairment and Alzheimer's disease

Meritxell Bach Cuadra, Bénédicte Marie Maréchal, Delphine Ribes Lemay, Alessandro Daducci, Reto Meuli, Cristina Granziera, Gunnar Krüger, Daniel Andreas Schmitter, Alexis Roche, Ahmed Abdulkadir

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer’s disease (AD) related brain atrophy and to enable fairly accurate automated classification of AD patients, mild cognitive impaired patients (MCI) and e ...

Elsevier2015

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing‐remitting multiple sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Jonas Richiardi, Gunnar Krüger, Alexis Roche, Guillaume Bonnier

Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

Wiley-Blackwell2015

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Gloria Menegaz

Objectives: Contralesional brain connectivity plasticity was previously reported after stroke. This study aims at disentangling the biological mechanisms underlying connectivity plasticity in the uninjured motor network after an ischemic lesion. In particu ...

2015

Multicontrast MRI Quantification of Focal Inflammation and Degeneration in Multiple Sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Introduction. Local microstructural pathology in multiple sclerosis patients might influence their clinical performance. This study applied multicontrast MRI to quantify inflammation and neurodegeneration in MS lesions. We explored the impact of MRI-based ...

Hindawi Publishing Corporation2015

Prospective motion correction with FID-triggered image navigators

Jean-Philippe Thiran, Rolf Gruetter, Tobias Kober, Tom Hilbert, Reto Meuli, Gunnar Krüger, Guillaume Bonnier, Pavel Falkovskiy, Maryna Volodimirivna Waszak

2015