Publications de Georgios Papadopoulos

A Combination of Cold Ion Spectroscopy and Ion Mobility for the Study of Complex Peptides and Small Proteins

We present in this work experiments that push the limits of cold ion spectroscopy to the study of complex peptides and small proteins in the gas phase. Although the low temperature attainable in a cold ion trap greatly simplifies the electronic spectra of ...

EPFL2012

Conformational distribution of bradykinin [bk+2H]2+ revealed by cold ion spectroscopy coupled with FAIMS

Thomas Rizzo, Oleg Boyarkine, Annette Svendsen, Georgios Papadopoulos

We employ Cold Ion Spectroscopy (CIS) in conjunction with high-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) to study the peptide bradykinin in its doubly protonated charge state ([bk+2H]2+). Using FAIMS we partially separate the electrospray ...

Springer-Verlag2012

Spectroscopy of mobility-selected biomolecular ions

Thomas Rizzo, Oleg Boyarkine, Annette Svendsen, Georgios Papadopoulos

We describe here experiments that combine differential ion mobility, which separates conformational isomers of biomolecular ions, with electronic spectroscopy in a cold, radio-frequency ion trap. Although the low temperature attainable in a cold ion trap g ...

2011

Spectroscopy of Protonated Peptides Assisted by Infrared Multiple Photon Excitation

Thomas Rizzo, Ulrich Lorenz, Oleg Boyarkine, Monia Guidi, Georgios Papadopoulos

We report here a new technique for spectroscopic studies of protonated, gas- phase biomolecules and demonstrate its utility by measuring highly-resolved electronic and infrared spectra of peptides of up to 17 amino acids. After UV excitation of an aromatic ...

2009