Mor-Miri Mishkovsky

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Publications associées (41)

Hyperpolarized 6Li as a probe for hemoglobin oxygenation level

Rolf Gruetter, Mor-Miri Mishkovsky, Arnaud Comment, Ruud van Heeswijk, Riccardo Balzan

Hyperpolarization by dissolution dynamic nuclear polarization (DNP) is a versatile technique to dramatically enhance the nuclear magnetic resonance (NMR) signal intensity of insensitive long-T1 nuclear spins such as 6 Li. The 6 Li longitudinal relaxation o ...

Wiley-Blackwell2016

Producing Radical-Free Hyperpolarized Perfusion Agents for In Vivo Magnetic Resonance Using Spin-Labeled Thermoresponsive Hydrogel

Mor-Miri Mishkovsky, Tian Cheng, Arnaud Comment

Dissolution dynamic nuclear polarization (DNP) provides a way to tremendously improve the sensitivity of nuclear magnetic resonance experiments. Once the spins are hyperpolarized by dissolution DNP, the radicals used as polarizing agents become undesirable ...

Wiley-Blackwell2016

Studying glioblastoma progression in a rat model of human glioma initiating cells using 1H MRS and DTI

Rolf Gruetter, Cristina Ramona Cudalbu, Mor-Miri Mishkovsky, Arnaud Comment, Emine Can

2014

Purely endogenous hyperpolarized [1-13C]Pyruvate solutions for metabolic study in glioblastoma rat models

Rolf Gruetter, Mor-Miri Mishkovsky, Arnaud Comment, Emine Can, Tim Rolf Eichhorn

2014

Automated transfer and injection of hyperpolarized molecules with polarization measurement prior to in vivo NMR

Mor-Miri Mishkovsky, Tian Cheng, Arnaud Comment, Josefina Adriana Maria Bastiaansen

Hyperpolarized magnetic resonance via dissolution dynamic nuclear polarization necessitates the transfer of the hyperpolarized molecules from the polarizer to the imager prior to in vivo measurements. This process leads to unavoidable losses in nuclear pol ...

2013

Brain metabolism in rat model of human glioma initiating cells

Rolf Gruetter, Cristina Ramona Cudalbu, Mor-Miri Mishkovsky, Arnaud Comment

2013

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Rolf Gruetter, Mor-Miri Mishkovsky, João Miguel das Neves Duarte, Tian Cheng, Josefina Adriana Maria Bastiaansen, Arnaud Comment

BACKGROUND: Acetate metabolism in skeletal muscle is regulated by acetylCoA synthetase (ACS). The main function of ACS is to provide cells with acetylCoA, a key molecule for numerous metabolic pathways including fatty acid and cholesterol synthesis and the ...

Elsevier Science Bv2013

Hyperpolarization without persistent radicals for in vivo real-time metabolic imaging

Mor-Miri Mishkovsky, Christophe Roussel, Andrea Capozzi, Jean-Noël Hyacinthe, Tian Cheng, Arnaud Comment, Najat Salameh, Yuhei Takado, Tim Rolf Eichhorn

Hyperpolarized substrates prepared via dissolution dynamic nuclear polarization have been proposed as magnetic resonance imaging (MRI) agents for cancer or cardiac failure diagnosis and therapy monitoring through the detection of metabolic impairments in v ...

National Academy of Sciences2013

Bioreactor to simultaneously measure three parallel in vitro preparations

Rolf Gruetter, Mor-Miri Mishkovsky, Yves Pilloud, Arnaud Comment, Emine Can, Leila Drissi Daoudi - Kleinbauer, Riccardo Balzan

2013

Localized in vivo hyperpolarization transfer sequences

Rolf Gruetter, Mor-Miri Mishkovsky, Tian Cheng, Arnaud Comment

In vivo localized and fully adiabatic homonuclear and heteronuclear polarization transfer experiments were designed and performed in the rat brain at 9.4 T after infusion of hyperpolarized sodium [1,2-(13) C(2) ] and sodium [1-(13) C] acetate. The method p ...

Wiley-Blackwell2012

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Producing Radical-Free Hyperpolarized Perfusion Agents for In Vivo Magnetic Resonance Using Spin-Labeled Thermoresponsive Hydrogel

Mor-Miri Mishkovsky, Tian Cheng, Arnaud Comment

Wiley-Blackwell2016

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Rolf Gruetter, Mor-Miri Mishkovsky, João Miguel das Neves Duarte, Tian Cheng, Josefina Adriana Maria Bastiaansen, Arnaud Comment

Elsevier Science Bv2013