Liang Qiao

Cette personne n’est plus à l’EPFL

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Publications associées (47)

Multiple scanning electrochemical microscopy mapping of tyrosinase in micro-contact printed fruit samples on polyvinylidene fluoride membrane

Hubert Girault, Andreas Stephan Lesch, Liang Qiao, Fernando Cortes Salazar, Tzu-En Lin, Alexandra Bondarenko

Herein, we introduce three orthogonal and compatible methods for detecting tyrosinase, a key factor in fruit browning and skin disorders, with high spatial resolution by means of scanning electrochemical microscopy (SECM). All methods are performed subsequ ...

Elsevier2015

Ambient in situ analysis and imaging of both hydrophilic and hydrophobic thin layer chromatography plates by electrostatic spray ionization mass spectrometry

Hubert Girault, Liang Qiao, Xiaoqin Zhong

Electrostatic spray ionization (ESTASI) mass spectrometry imaging (MSI), recently developed to profile spatial distribution of chemical and biochemical molecules on an insulating surface under ambient conditions, has been applied to identify and quantify c ...

RSC Publishing2015

Porous silica enhanced proteolysis during Off-Gel separation for efficient protein identification

Hubert Girault, Liang Qiao, Mohammad Reza Pourhaghighi

An advanced approach is developed in this work for simultaneous on-line separation and digestion of proteins by combining the Off-Gel isoelectric focusing (IEF) and enzymatic nanoreactor enhanced proteolysis. The nanoreactor was prepared by preloading tryp ...

Elsevier2015

Standard addition strip for quantitative electrostatic spray ionization mass spectrometry analysis: Determination of caffeine in drinks

Hubert Girault, Christophe Roussel, Liang Qiao, Elena Tobolkina

Standard addition strips were prepared for the quantitative determination of caffeine in different beverages by electrostatic spray ionisation mass spectrometry (ESTASI-MS). The gist of this approach is to dry spots of caffeine solutions with different con ...

Elsevier2014

Surprising acidity of hydrated lithium cations in organic solvents

Hubert Girault, Liang Qiao, Pekka Eero Peljo, Thomas James Stockmann, Haiqiang Deng

Lithium cations are shown to have a significant role on catalyzing oxygen and proton reduction along with SN1 reactions in biphasic systems. We propose that this catalytic effect is due to the surprising acidity of the hydrated cations; interactions betwee ...

Royal Society of Chemistry2014

Fingerprinting the Tertiary Structure of Electroadsorbed Lysozyme at Soft Interfaces by Electrostatic Spray Ionization Mass Spectrometry

Hubert Girault, Liang Qiao, Micheal Diarmaid Scanlon

Lysozyme can be electrochemically detected after adsorption at an electrified gel-water interface. Ex-situ characterization by electrostatic spray ionization mass spectrometry provides insights into the interfacial detection mechanism by allowing changes t ...

Royal Society of Chemistry2014

On-Chip Spyhole Mass Spectrometry for Droplet-Based Microfluidics

Hubert Girault, Natalia Gasilova, Liang Qiao, Qiuliyang Yu

For efficient coupling of droplet-based microfluidics with mass spectrometry (MS), a spyhole drilled on the top of a microchip is used to sample the passing droplets by electrostatic-spray ionization (ESTASI) MS. The technique involves placing an electrode ...

Wiley-VCH Verlag GmbH2014

An Efficient Drug Metabolism Strategy Based on Microsome-Mesoporous Organosilica Nanoreactors

Hubert Girault, Liang Qiao, Peng Zhang

A rapid and accurate in-vitro drug metabolism strategy has been proposed based on the design of a biomimetic nanoreactor composed of amino-functionalized periodic mesoporous organosilica (NH2-PMO) and microsomes. The amphiphilic and positive charged NH2-PM ...

Amer Chemical Soc2014

Highly sensitive detection of five typical fluoroquinolones in low-fat milk by field-enhanced sample injection based CE in bubble cell capillary

Hubert Girault, Natalia Gasilova, Liang Qiao, Yan Deng

Fluoroquinolones are a group of synthetic antibiotics with a broad activity spectrum against mycoplasma, gram-positive and gram-negative bacteria. Due to the extensive use of fluoroquinolones in farming and veterinary science, there is a constant need in t ...

Wiley-Blackwell2014

Electrostatic Spray Ionization Mass Spectrometry Imaging

Hubert Girault, Horst Vogel, Horst Pick, Andreas Stephan Lesch, Liang Qiao, Alexandra Bondarenko, Elena Tobolkina, Xiaoqin Zhong

Imaging samples on a surface by mass spectrometry (MS) requires the combination of MS detection with a scanning mode that enables localized desorption and ionization and/or detection of sample analytes with good spatial resolution. We have developed a new ...

Amer Chemical Soc2014

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