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Julita Maria Stadnicka-Michalak

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Publications associées (6)

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Predicting exposure concentrations of chemicals with a wide range of volatility and hydrophobicity in different multi-well plate set-ups

Kristin Schirmer, Julita Maria Stadnicka-Michalak

Quantification of chemical toxicity in small-scale bioassays is challenging owing to small volumes used and extensive analytical resource needs. Yet, relying on nominal concentrations for effect determination maybe erroneous because loss processes can sign ...

NATURE RESEARCH2021

Gut microbial transformation of the dietary mutagen MeIQx may reduce exposure levels without altering intestinal transport

Julita Maria Stadnicka-Michalak, Jianbo Zhang

The mutagen and probable human carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) is metabolized in the colon to 9-hydroxyl-2,7-dimethyl-7,9,10,11-tetrahydropyrimido[2',1':2,3]imidazo[4,5-f]quinoxaline (MeIQx-M1) by conjugation with microbial ...

PERGAMON-ELSEVIER SCIENCE LTD2019

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Principles for determining uptake kinetics and bioconcentration factors for nanoparticles and test organisms have only been cursorily explored. Here we report the derivation of bioconcentration factors (BCFs) and the role of surface functionalization in th ...

Royal Soc Chemistry2017

Tralopyril bioconcentration and effects on the gill proteome of the Mediterranean mussel Mytilus galloprovincialis

Julita Maria Stadnicka-Michalak, Kevin Thomas

Antifouling (AF) systems are used worldwide as one of the most cost-effective ways of protecting submerged structures against heavy biofouling. The emergence of environmentally friendly AF biocides requires knowledge on their environmental fate and toxicit ...

Elsevier Science Bv2016

Zebrafish (Danio rerio) larvae have been suggested as vertebrate model to complement or even replace mammals for rapidly assessing behavioral effects of psychoactive drugs. Yet, divergent responses have been reported in mammals and fish despite the conserv ...

Oxford Univ Press2016

Effect concentrations in the toxicity assessment of chemicals with fish and fish cells are generally based on external exposure concentrations. External concentrations as dose metrics, may, however, hamper interpretation and extrapolation of toxicological ...

Public Library Science2014