Alexis Roche

Cette personne n’est plus à l’EPFL

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Publications associées (26)

Cerebellar Connectomics Provide New Biomarkers in Early Multiple Sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano, Alessandro Daducci, Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alexis Roche, Jonas Richiardi, Guillaume Bonnier

The cerebellum is involved in multiple sclerosis (MS), but its implication in early phases is still poorly understood. We investigated structural and functional cerebellar connectivity alterations in early and minimally impaired MS patients, and their corr ...

2014

Robust T1-Weighted Structural Brain Imaging and Morphometry at 7T Using MP2RAGE

Tobias Kober, Patric Hagmann, Gunnar Krüger, José Pedro Rebelo Ferreira Marques, Alexis Roche, Kieran O'Brien, François Lazeyras

Purpose To suppress the noise, by sacrificing some of the signal homogeneity for numerical stability, in uniform T1 weighted (T1w) images obtained with the magnetization prepared 2 rapid gradient echoes sequence (MP2RAGE) and to compare the clinical utilit ...

Public Library of Science2014

Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

2014

A simple method to denoise ratio images in magnetic resonance imaging

Alexis Roche, Kieran O'Brien

Disclosed is a Magnetic Resonance Imaging method comprising the steps of: generating an MRI sequence designed for acquiring data from an object to be imaged, wherein the MRI sequence is configured for generating at least two different standard images, resp ...

2014

Volume-based vs. voxel-based brain morphometry in Alzheimer's disease prediction

Meritxell Bach Cuadra, Bénédicte Marie Maréchal, Delphine Ribes Lemay, Reto Meuli, Alessandro Daducci, Cristina Granziera, Daniel Andreas Schmitter, Gunnar Krüger, Alexis Roche, Ahmed Abdulkadir

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer's disease (AD) related brain atrophy and to enable accurate automated classification of AD patients, mild cognitive impaired (MCI) patients and elderly ...

Proceedings of 23rd International Society for Magnetic Resonance in Medicine (ISMRM) Conference2014

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Jean-Philippe Thiran, David Paul Roger Romascano, Djalel Eddine Meskaldji, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014

Structural abnormalities in the thalamus of migraineurs with aura: a multiparametric study at 3T

David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Nouchine Hadjikhani, Gunnar Krüger, Alexis Roche

Background and objectives: The thalamus exerts a pivotal role in pain processing and cortical excitability control, and migraine is characterized by repeated pain attacks and abnormal cortical habituation to excitatory stimuli. This work aimed at studying ...

Wiley-Blackwell2013

A simple method to denoise MP2RAGE

Rolf Gruetter, Gunnar Krüger, Alexis Roche, Kieran O'Brien, François Lazeyras

2013

Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Tobias Kober, Reto Meuli, Alessandro Daducci, Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alexis Roche, François Lazeyras

Objective Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an innovative multi-contrast magnetic resonance imaging (MRI) approach at high-field to assess ...

Public Library of Science2013

Migraineurs without aura show microstructural abnormalities in the cerebellum and frontal lobe

David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Nouchine Hadjikhani, Gunnar Krüger, Alexis Roche

The involvement of the cerebellum in migraine pathophysiology is not well understood. We used a biparametric approach at high-field MRI (3 T) to assess the structural integrity of the cerebellum in 15 migraineurs with aura (MWA), 23 migraineurs without aur ...

Springer US2013

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Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Tobias Kober, Reto Meuli, Alessandro Daducci, Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alexis Roche, François Lazeyras

Public Library of Science2013

Migraineurs without aura show microstructural abnormalities in the cerebellum and frontal lobe

David Paul Roger Romascano, Alessandro Daducci, Cristina Granziera, Nouchine Hadjikhani, Gunnar Krüger, Alexis Roche

Springer US2013