Personne

Thanh-An Michel Pham

Publications associées (13)

Phase Retrieval: From Computational Imaging to Machine Learning: A tutorial

Michaël Unser, Thanh-An Michel Pham, Jonathan Yuelin Dong

Phase retrieval consists in the recovery of a complex-valued signal from intensity-only measurements. As it pervades a broad variety of applications, many researchers have striven to develop phase-retrieval algorithms. Classical approaches involve techniqu ...
2023

Nonlinear Inverse Problems in Quantitative Phase Imaging

Thanh-An Michel Pham

The topic of this thesis is the development of new algorithmic reconstruction methods for quantitative phase imaging (QPI). In the past decade, advanced QPI has emerged as a valuable tool to study label-free biological samples and uncover their 3D structur ...
EPFL2022

Bayesian Inversion for Nonlinear Imaging Models Using Deep Generative Priors

Michaël Unser, Thanh-An Michel Pham, Pakshal Narendra Bohra, Jonathan Yuelin Dong

Most modern imaging systems incorporate a computational pipeline to infer the image of interest from acquired measurements. The Bayesian approach to solve such ill-posed inverse problems involves the characterization of the posterior distribution of the im ...
2022

Optical diffraction tomography from single-molecule localization microscopy

Michaël Unser, Thanh-An Michel Pham, Emmanuel Emilien Louis Soubies, Ferréol Arnaud Marie Soulez

Single-molecule localization microscopy (SMLM) is a powerful method for the imaging of cellular structures. This modality delivers nanoscale resolution by sequentially activating a subset of fluorescent molecules and by extracting their super-resolved posi ...
2021

Robust Phase Unwrapping via Deep Image Prior for Quantitative Phase Imaging

Michaël Unser, Matthias Lütolf, Nathalie Brandenberg, Thanh-An Michel Pham, Fangshu Yang

Quantitative phase imaging (QPI) is an emerging label-free technique that produces images containing morphological and dynamical information without contrast agents. Unfortunately, the phase is wrapped in most imaging system. Phase unwrapping is the comput ...
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Diffraction Tomography from Single-Molecule Localization Microscopy: Numerical Feasibility

Michaël Unser, Thanh-An Michel Pham, Emmanuel Emilien Louis Soubies, Ferréol Arnaud Marie Soulez

Single-molecule localization microscopy (SMLM) is a fluorescence microscopy technique that achieves super-resolution imaging by sequentially activating and localizing random sparse subsets of fluorophores. Each activated fluorophore emits light that then s ...
IEEE2021

Deep-learning projector for optical diffraction tomography

Michaël Unser, Thanh-An Michel Pham, Harshit Gupta, Fangshu Yang

Optical diffraction tomography is an effective tool to estimate the refractive indices of unknown objects. It proceeds by solving an ill-posed inverse problem for which the wave equation governs the scattering events. The solution has traditionally been de ...
OPTICAL SOC AMER2020

Adaptive Regularization For Three-Dimensional Optical Diffraction Tomography

Michaël Unser, Demetri Psaltis, Thanh-An Michel Pham, Emmanuel Emilien Louis Soubies, Ahmed Ayoub

Optical diffraction tomography (ODT) allows one to quantitatively measure the distribution of the refractive index of the sample. It relies on the resolution of an inverse scattering problem. Due to the limited range of views as well as optical aberrations ...
IEEE2020

Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

Michaël Unser, Daniel Sage, Thanh-An Michel Pham, Tomas Lukes, Seamus John Holden, Anna Archetti, Thomas Pengo, Ricardo Henriques, Silvia Colabrese, Anurag Agrawal

With the widespread uptake of two-dimensional (2D) and three-dimensional (3D) single-molecule localization microscopy (SMLM), a large set of different data analysis packages have been developed to generate super-resolution images. In a large community effo ...
2019

Pocket guide to solve inverse problems with GlobalBioIm

Michaël Unser, Daniel Sage, Thanh-An Michel Pham, Laurène Donati, Emmanuel Emilien Louis Soubies, Ferréol Arnaud Marie Soulez, Michael Thompson McCann, Thomas Jean Debarre

GlobalBioIm is an open-source MATLAB (R) library for solving inverse problems. The library capitalizes on the strong commonalities between forward models to standardize the resolution of a wide range of imaging inverse problems. Endowed with an operator-al ...
IOP PUBLISHING LTD2019

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