Publications de Nima Aliakbarinodehi

Direct and catalyst-free growth of vertically-stacked graphene-based structures for enhanced drug sensing

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

In this work, a complete study is carried out for the optimised, direct and catalyst-free growth of vertically-stacked graphene-based structures targeting at improved performance drug monitoring. The nanostructures, ultimately forming a honeycomb network o ...

IEEE2019

Graphene nanowalls for high-performance chemotherapeutic drug sensing and anti-fouling properties

Giovanni De Micheli, Ioulia Tzouvadaki, Sandro Carrara, Nima Aliakbarinodehi

Improved sensitivity and continuous monitoring of therapeutic compounds are two of the most highlighted concerns for the treatment of malignant diseases, such as cancer. We demonstrated ultrasensitive screening of etoposide, a therapeutic compound widely-u ...

2018

Highly sensitive enzymatic MWCNTs-based biosensors for detection of abiraterone in human serum

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

A highly-sensitive enzymatic biosensor is successfully experimented for detection of abiraterone in human serum with significance in personalized medicine and point-of-care chemotherapy of patients with metastatic prostate cancer. The dynamic range and lim ...

2018

Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum

Giovanni De Micheli, Nima Aliakbarinodehi, Sandro Carrara, Francesca Stradolini, Irene Taurino, Ioulia Tzouvadaki, Sattar Akbari Nakhjavani

Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the Electro-Active Surface Area (EASA). In this work, an analytical calculation of the deposited EASA is presented and experimentally validated b ...

2018

Aptamer-based Field-Effect Biosensor for Tenofovir Detection

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

During medical treatment it is critical to maintain the circulatory concentration of drugs within their therapeutic range. A novel biosensor is presented in this work to address the lack of a reliable point-of-care drug monitoring system in the market. The ...

Nature Research2017

Ultra Selective and Sensitive Electrochemical Detection of Anti-Cancer and Anti-Viral Drugs by Optimized Nano-Bio-Sensors

Nima Aliakbarinodehi

Reliable, low cost, and accessible drug monitoring systems for individualized healthcare, especially chemotherapy for malignant diseases like prostate cancer and AIDS, are highly desira-ble. This is even more critical for drugs like abiraterone and TFV, wi ...

EPFL2017

The memristive effect as a novelty in drug monitoring

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Nima Aliakbarinodehi

Nanoscale devices exhibiting memristive properties show great potential in a plethora of applications. In this work, memristive nanowires are presented for the first time as ideal candidates for absolutely novel, ultrasensitive, highly specific and selecti ...

2017

Memristive Aptasensors for Theranostics

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Nima Aliakbarinodehi

A new application in the nano-biosensing field gives proof that the coupling of nanofabricated wires exhibiting mem- ristive electrical characteristics and DNA-aptamers, may provide definitely innovative nano-bio-sensors for ultrasensitive label-free detec ...

2017

Optimized Electrochemical Detection of Anti-Cancer Drug by Carbon Nanotubes or Gold Nanoparticles

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

Nanostructured biosensors with the aim of electroactive cancer-drug detection were investigated. The aim of this work is improvement of the sensitivity and limit of detection of two differently nanostructured biosensors to find out the best choice for quan ...

2015

Electrochemical nanostructured biosensors: carbon nanotubes versus conductive and semi-conductive nanoparticles

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Nima Aliakbarinodehi, Gianluca Piccinini

The aim of this work was to demonstrate that various types of nanostructures provide different gains in terms of sensitivity or detection limit albeit providing the same gain in terms of increased area. Commercial screen printed electrodes (SPEs) were func ...

De Gruyter Open Ltd2015