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Grigory Karateev

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Publications associées (6)

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Molecular imaging allows noninvasive visualization of biological processes in their native environment within living systems. It can give a better understanding of fundamental biology, help in identifying disease mechanisms and visualizing pathological tis ...

EPFL2019

A System for In Vivo Imaging of Hepatic Free Fatty Acid Uptake

Grigory Karateev

Alterations in hepatic free fatty acid (FFA) uptake and metabolism contribute to the development of prevalent liver disorders such as hepatosteatosis. However, detecting dynamic changes in FFA uptake by the liver in live model organisms has proven difficul ...

Elsevier2017

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Bacterial nitroreductases (NTRs) have been widely utilized in the development of novel antibiotics, degradation of pollutants, and gene-directed enzyme prodrug therapy (GDEPT) of cancer that reached clinical trials. In case of GDEPT, since NTR is not natur ...

Public Library of Science2015

Matrix-Assisted Transplantation of Functional Beige Adipose Tissue

Riccardo Sinisi, Grigory Karateev

Novel, clinically relevant, approaches to shift energy balance are urgently needed to combat metabolic disorders such as obesity and diabetes. One promising approach has been the expansion of brown adipose tissues that express uncoupling protein (UCP) 1 an ...

American Diabetes Association2015

The ability of white and brown adipose tissue to efficiently take up long-chain fatty acids is key to their physiological functions in energy storage and thermogenesis, respectively. Several approaches have been taken to determine uptake rates by cultured ...

Elsevier Academic Press Inc2014

Bioluminescence imaging of small biomolecules

Aurélien Godinat, Riccardo Sinisi, Grigory Karateev, Ghyslain Martial Alain Budin, Aleksandra Konovalova, Jens Tomas Frigell

The invention relates to a technique to detect small molecules using Bioluminescence imaging (BLI) to image and quantify non-invasively, in vitro and in vivo,intracellular metabolite fluxes and which can be applied to azido-modified compounds, such as azid ...

2014