Publications de Marco Capogrosso

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease

Auke Ijspeert, Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Eduardo Martin Moraud, Jordan Squair, Giuseppe Schiavone, Léonie Asboth, Tomislav Milekovic

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor deficits that are resistant to currently available therapies. To alleviate these deficits, we developed a neuroprosthesis operating in closed loop that targets the dor ...

Nature Portfolio2023

Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Grégoire Courtine, Jocelyne Bloch, Quentin Barraud, Léonie Asboth, Robin Jonathan Demesmaeker, Nawal Noëlle Kinany, Miroslav Caban, Sergio Daniel Hernandez

Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments restores walking in people with spinal cord injury (SCI). However, EES is delivered with multielectrode paddle leads that were originally designed to target the dorsal ...

NATURE PORTFOLIO2022

System for planning and/or providing neuromodulation

Grégoire Courtine, Vincent Delattre, Marco Capogrosso, Fabien Bertrand Paul Wagner, Karen Minassian

The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includesa stimulation related basic data storage module for storing stimulation related basic data,a stimulation related response data sto ...

2021

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Eduardo Martin Moraud, Quentin Barraud, Jordan Squair, Giuseppe Schiavone, Ileana Ozana Jelescu, Mark Andrew Anderson, Robin Jonathan Demesmaeker

Spinal cord injury (SCI) induces haemodynamic instability that threatens survival(1-3), impairs neurological recovery(4,5), increases the risk of cardiovascular disease(6,7), and reduces quality of life(8,9). Haemodynamic instability in this context is due ...

NATURE RESEARCH2021

Spatiotemporal Maps of Proprioceptive Inputs to the Cervical Spinal Cord During Three-Dimensional Reaching and Grasping

Auke Ijspeert, Shravan Tata Ramalingasetty, Marco Capogrosso, Nathan Antoine Greiner, Beatrice Barra, Pierre Charles Marie Kibleur, Sara Conti

Proprioceptive feedback is a critical component of voluntary movement planning and execution. Neuroprosthetic technologies aiming at restoring movement must interact with it to restore accurate motor control. Optimization and design of such technologies de ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Soft, Implantable Bioelectronic Interfaces for Translational Research

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Jocelyne Bloch, Ismael Seanez Gonzalez, Sébastien Jiguet, Ivan Furfaro, Simon Borgognon, Evgenia Vladimirova Roussinova, Marco Capogrosso

The convergence of materials science, electronics, and biology, namely bioelectronic interfaces, leads novel and precise communication with biological tissue, particularly with the nervous system. However, the translation of lab‐based innovation toward cli ...

Wiley2020

A system for providing neuromodulation, especially neurostimulation

Grégoire Courtine, Marco Capogrosso, Beatrice Barra, Katie Zhi Zhuang

A system (10) for providing neuromodulation, especially neurostimulation, comprising - at least one neuromodulator (12) for neuromodulation of the cervical spinal cord, - at least one dorsal neuromodulation array (14) for providing neuromodulation to the c ...

2020

A versatile robotic platform for the design of natural, three-dimensional reaching and grasping tasks in monkeys

Aude Billard, Silvestro Micera, Marco Capogrosso, Seyed Sina Mirrazavi Salehian, Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Sara Conti

Objective. Translational studies on motor control and neurological disorders require detailed monitoring of sensorimotor components of natural limb movements in relevant animal models. However, available experimental tools do not provide a sufficiently ric ...

IOP PUBLISHING LTD2020

Automatic clustering of spinal reflexes evoked by epidural electrical stimulation of the cervical spinal cord in non-human primates

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Jocelyne Bloch, Marco Capogrosso, Beatrice Barra, Katie Zhi Zhuang, Sara Conti

Epidural electrical stimulation of the spinal cord elicits motor responses by recruiting large sensory afferents in the posterior roots. Divergence of excitatory inputs provided by these fibers generates a variety of shapes, latencies and amplitudes in the ...

2019

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Silvestro Micera, Stanisa Raspopovic, Marco Capogrosso, Francesco Maria Petrini, Jacopo Rigosa, Beatrice Barra, Alessandra Pampaloni

Background:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the process-ing of descending efferent neural signals recorded using peripheral neural interfaces ...

2019