Publications de Oren Amsalem | EPFL Graph Search

Thalamic control of sensory processing and spindles in a biophysical somatosensory thalamoreticular circuit model of wakefulness and sleep

Henry Markram, Sean Lewis Hill, Michael Reimann, Rodrigo de Campos Perin, James Gonzalo King, Ying Shi, Rajnish Ranjan, Mustafa Anil Tuncel, Samuel Claude Kerrien, Polina Litvak

2023

Statistical Emulation of Neural Simulators: Application to Neocortical L2/3 Large Basket Cells

Idan Segev, Werner Alfons Hilda Van Geit, Oren Amsalem

Many scientific systems are studied using computer codes that simulate the phenomena of interest. Computer simulation enables scientists to study a broad range of possible conditions, generating large quantities of data at a faster rate than the laboratory ...

FRONTIERS MEDIA SA2022

The Role of Hub Neurons in Modulating Cortical Dynamics

Henry Markram, Felix Schürmann, Idan Segev, Oren Amsalem, Eyal Gal, Michael London

Many neurodegenerative diseases are associated with the death of specific neuron types in particular brain regions. What makes the death of specific neuron types particularly harmful for the integrity and dynamics of the respective network is not well unde ...

2021

An efficient analytical reduction of detailed nonlinear neuron models

Felix Schürmann, Idan Segev, Pramod Shivaji Kumbhar, Michael Emiel Gevaert, Oren Amsalem, Guy Eyal

Detailed conductance-based nonlinear neuron models consisting of thousands of synapses are key for understanding of the computational properties of single neurons and large neuronal networks, and for interpreting experimental results. Simulations of these ...

Nature Research2020

From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

Henry Markram, Eilif Benjamin Muller, Idan Segev, Werner Alfons Hilda Van Geit, Oren Amsalem

In the neocortex, inhibitory interneurons of the same subtype are electrically coupled with each other via dendritic gap junctions (GJs). The impact of multiple GJs on the biophysical properties of interneurons and thus on their input processing is unclear ...

Oxford University Press (OUP)2016