Publications de Blanca Lizarbe Serra

Excitatory/inhibitory neuronal metabolic balance in mouse hippocampus upon infusion of [U-C-13(6)]glucose

Rolf Gruetter, Bernard Lanz, Hongxia Lei, Carole Poitry-Yamate, Antoine Timothée Cherix, Guillaume Donati, Blanca Lizarbe Serra

Hippocampus plays a critical role in linking brain energetics and behavior typically associated to stress exposure. In this study, we aimed to simultaneously assess excitatory and inhibitory neuronal metabolism in mouse hippocampus in vivo by applying (18) ...

2021

High-fat diet consumption alters energy metabolism in the mouse hypothalamus

Rolf Gruetter, João Miguel das Neves Duarte, Antoine Timothée Cherix, Blanca Lizarbe Serra, Jean-René Cardinaux

BACKGROUND/OBJECTIVES: High-fat diet consumption is known to trigger an inflammatory response in the hypothalamus, which has been characterized by an initial expression of pro-inflammatory genes followed by hypothalamic astrocytosis, microgliosis, and the ...

2019

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

João Miguel das Neves Duarte, Ana Francisca Leal Silva Soares, Blanca Lizarbe Serra

Metabolic syndrome and diabetes impact brain function and metabolism. While it is well established that rodents exposed to diets rich in saturated fat develop brain dysfunction, contrasting results abound in the literature, likely as result of exposure to ...

2019

Metabolic alterations in the hippocampus, cortex and hypothalamus of mice exposed to long-term high-fat diet

João Miguel das Neves Duarte, Ana Francisca Leal Silva Soares, Blanca Lizarbe Serra

SAGE PUBLICATIONS INC2019

Feasibility of in vivo measurement of glucose metabolism in the mouse hypothalamus by (1) H-[(13) C] MRS at 14.1T

Rolf Gruetter, Bernard Lanz, João Miguel das Neves Duarte, Hongxia Lei, Antoine Timothée Cherix, Blanca Lizarbe Serra

PURPOSE: Determine the feasibility of (1) H-[(13) C] MRS in the mouse hypothalamus using a 14.1T magnet. METHODS: We optimized the design of a (1) H-[(13) C] surface coil to maximize the signal-to-noise ratio of (1) H-[(13) C] MRS in the mouse hypothalamus ...

Wiley2018

In vivo detection of hypothalamic glucose metabolism in HFD and regular fed mice

Rolf Gruetter, Hongxia Lei, Antoine Timothée Cherix, Blanca Lizarbe Serra

Sage Publications Inc2017

Defining mitochondrial biomarkers and function using magnetic resonance spectroscopy at 14.1 Tesla in a mouse model of mood disorders

Rolf Gruetter, Hongxia Lei, Antoine Timothée Cherix, Guillaume Donati, Blanca Lizarbe Serra

Sage Publications Inc2017

Investigating mitochondrial biomarkers and function using MRS at 14.1 Tesla in a mouse model of mood disorders

Rolf Gruetter, Hongxia Lei, Antoine Timothée Cherix, Guillaume Donati, Blanca Lizarbe Serra

Wiley2017