Publications de Max Christian Nolte

Impact of higher order network structure on emergent cortical activity

Henry Markram, Michael Reimann, Max Christian Nolte

Synaptic connectivity between neocortical neurons is highly structured. The network structure of synaptic connectivity includes first-order properties that can be described by pairwise statistics, such as strengths of connections between different neuron t ...

2020

Untangling emergent cortical dynamics: neurons from networks, noise from chaos

Max Christian Nolte

The way in which cortical microcircuit components -- most importantly neurons -- and their connectivity -- the network -- shape and constrain emergent dynamics is a long-standing question in neuroscience. Experimentally observed dynamical properties can of ...

EPFL2019

Cortical reliability amid noise and chaos

Henry Markram, Eilif Benjamin Muller, Michael Reimann, James Gonzalo King, Max Christian Nolte

Typical responses of cortical neurons to identical sensory stimuli appear highly variable. It has thus been proposed that the cortex primarily uses a rate code. However, other studies have argued for spike-time coding under certain conditions. The potentia ...

Nature Research2019

Generating and identifying functional subnetworks within structural networks

Henry Markram, Kathryn Hess Bellwald, Michael Reimann, Ran Levi, Max Christian Nolte

In one aspect, a method includes generating a functional subgraph of a network from a structural graph of the network. The structural graph comprises a set of vertices and structural connections between the vertices. Generating the functional subgraph incl ...

2018

Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function

Henry Markram, Kathryn Hess Bellwald, Rodrigo de Campos Perin, Michael Reimann, Giuseppe Chindemi, Martina Scolamiero, Max Christian Nolte, Ran Levi, Katharine Felicity Turner, Pawel Tadeusz Dlotko

The lack of a formal link between neural network structure and its emergent function has hampered our understanding of how the brain processes information. We have now come closer to describing such a link by taking the direction of synaptic transmission i ...

Frontiers Media Sa2017

Reconstruction and Simulation of Neocortical Microcircuitry

Anastasia Ailamaki, Henry Markram, Sean Lewis Hill, Eilif Benjamin Muller, Rodrigo de Campos Perin, Lida Kanari, Srikanth Ramaswamy, Vincent Delattre, Michael Reimann, Ying Shi

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of juvenile rat. The reconstruction uses cellular and synaptic organizing principles to algorithmically reconstruct detailed anatomy and physiology from sparse ex ...

Elsevier2015