Publications de Berna Ayse Özkale Edelmann

Actuated 3D microgels for single cell mechanobiology

Mahmut Selman Sakar, Ece Özelçi, Berna Ayse Özkale Edelmann, Christina Myra Tringides

We present a new cell culture technology for large-scale mechanobiology studies capable of generating and applying optically controlled uniform compression on single cells in 3D. Mesenchymal stem cells (MSCs) are individually encapsulated inside an optical ...

ROYAL SOC CHEMISTRY2022

Actuated 3D microgels for single cell mechanobiology (vol 22, pg 1962, 2022)

Mahmut Selman Sakar, Ece Özelçi, Berna Ayse Özkale Edelmann, Christina Myra Tringides

ROYAL SOC CHEMISTRY2022

Active biomaterials for mechanobiology

Mahmut Selman Sakar, Berna Ayse Özkale Edelmann

Active biomaterials offer novel approaches to study mechanotransduction in mammalian cells. These material systems probe cellular responses by dynamically modulating their resistance to endogenous forces or applying exogenous forces on cells in a temporall ...

2020

Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation

Berna Ayse Özkale Edelmann, Christina Myra Tringides

Mesenchymal stem cell (MSC) therapies demonstrate particular promise in ameliorating diseases of immune dysregulation but are hampered by short in vivo cell persistence and inconsistencies in phenotype. Here, we demonstrate that biomaterial encapsulation i ...

National Academy of Sciences2019

Modular soft robotic microdevices for dexterous biomanipulation

Francesco Stellacci, Mahmut Selman Sakar, Ece Özelçi, Ahmet Bekdemir, Murat Kaynak, Berna Ayse Özkale Edelmann, Raquel Filipa Penacho Parreira, Lucio Feo Pancaldi-Giubbini

We present a methodology for building biologically inspired, soft microelectromechanical systems (MEMS) devices. Our strategy combines several advanced techniques including programmable colloidal self-assembly, light-harvesting with plasmonic nanotransduce ...

2019

Robotically controlled microprey to resolve initial attack modes preceding phagocytosis

Mahmut Selman Sakar, Berna Ayse Özkale Edelmann

2017

Inkjet printed superparamagnetic polymer composite hemispheres with programmed magnetic anisotropy

Jürgen Brugger, Massimo Mastrangeli, Victor Javier Cadarso Busto, Christofer Hierold, Loïc Jacot-Descombes, Rosario Maurizio Gullo, Berna Ayse Özkale Edelmann

We present the fabrication and characterization of large arrays of inkjet-printed superparamagnetic polymer composite (SPMPC) hemispherical microstructures. SPMPCs are appealing for applications in microsystems and nanorobotics due to the added functionali ...

Royal Soc Chemistry2014