Publications de Elena Braconi | EPFL Graph Search

Chiral Diimine Complexes of Earth-Abundant Transition Metals for Asymmetric Catalysis

The application of Earth-abundant metals in asymmetric catalysis is key to transition towards a more sustainable chemistry. In particular, expanding the library of redox-active ligands capable of supporting Earth-abundant metals is essential in order to re ...

EPFL2022

Enantioselective Iron-Catalyzed Cross-[4+4]-Cycloaddition of 1,3-Dienes Provides Chiral Cyclooctadienes

Nicolai Cramer, Elena Braconi

Chiral cyclooctadienes are a frequently occurring scaffold in natural products and specialty chemicals, and are used as ligands in asymmetric catalysis. Accessing substituted cyclooctadienes in an efficient asymmetric fashion has been notoriously challengi ...

2020

A Chiral Naphthyridine Diimine Ligand Enables Nickel‐Catalyzed Asymmetric Alkylidenecyclopropanations

Nicolai Cramer, Elena Braconi

A novel class of chiral naphthyridine diimine ligands (NDI*) readily accessible from C2‐symmetric 2,6‐di‐(1‐arylethyl)anilines is described. The utility of these ligands, particularly one with fluorinated aryl side arms, is demonstrated by a reductive Ni‐c ...

Wiley-VCH Verlag GmbH2020

Axially Chiral Dibenzazepinones by a Palladium(0)-Catalyzed Atropo-enantioselective C-H Arylation

Nicolai Cramer, Matthew Wodrich, Christopher Gordon Newton, Elena Braconi, Jennifer Kuziola

Atropo‐enantioselective C−H functionalization reactions are largely limited to the dynamic kinetic resolution of biaryl substrates through the introduction of steric bulk proximal to the axis of chirality. Reported herein is a highly atropo‐enantioselectiv ...

Wiley-VCH Verlag GmbH2018