Publications de Andéol Geoffroy Cadic-Melchior

Brain Oscillatory Modes as a Proxy of Stroke Recovery

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Silvestro Micera, Friedhelm Christoph Hummel, Takuya Morishita, Elena Beanato, Sylvain Jean-François Harquel, Lisa Aïcha Mireille Julie Fleury, Nathalie Heidi Meyer, Maximilian Jonas Wessel

Background Stroke is the leading cause of long-term disability, making the search for successful rehabilitation treatment one of the most important public health issues. A better understanding of the neural mechanisms underlying impairment and recovery is ...

SAGE Publications2025

MEP and TEP features variability: is it just the brain-state?

Friedhelm Christoph Hummel, Estelle Emeline Raffin, Sylvain Jean-François Harquel, Andéol Geoffroy Cadic-Melchior, Michele Bevilacqua, Claudia Bigoni

Objective. The literature investigating the effects of alpha oscillations on corticospinal excitability is divergent. We believe inconsistency in the findings may arise, among others, from the electroencephalography (EEG) processing for brain-state determi ...

Iop Publishing Ltd2024

Native learning ability and not age determines the effects of brain stimulation

Friedhelm Christoph Hummel, Pablo Maceira Elvira, Traian Popa, Anne-Christine Schmid, Andéol Geoffroy Cadic-Melchior

Healthy aging often entails a decline in cognitive and motor functions, affecting independence and quality of life in older adults. Brain stimulation shows potential to enhance these functions, but studies show variable effects. Previous studies have tried ...

2024

Longitudinal evaluation of the mechanisms supporting post-stroke motor recovery using TMS-EEG coupling

Andéol Geoffroy Cadic-Melchior

Stroke is the main source of long-lasting disability, affecting dominantly motor functions. The extent and course of recovery are highly heterogeneous between patients, with a minority of patients fully recovering from their initial impairments, leaving 85 ...

EPFL2023

Differential Impact of Brain Network Efficiency on Poststroke Motor and Attentional Deficits

Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Gabriel Girard, Takuya Morishita, Elena Beanato, Lisa Aïcha Mireille Julie Fleury, Nathalie Heidi Meyer, Maximilian Jonas Wessel, Philip Egger, Philipp Johannes Koch

Background:Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often have multiple deficits in different domains. While the mechanisms underlying multiple-domain deficits remain poorly understood, network-theoretic ...

2023

The effect of gamified robot-enhanced training on motor performance in chronic stroke survivors

Pierre Dillenbourg, Friedhelm Christoph Hummel, Giulia Dominijanni, Barbara Bruno, Maximilian Jonas Wessel, Arzu Güneysu Özgür, Andéol Geoffroy Cadic-Melchior, Valérie Rita Madeleine Zufferey

Task-specific training constitutes a core element for evidence-based rehabilitation strategies targeted at improving upper extremity activity after stroke. Its combination with additional treatment strategies and neurotechnologybased solutions could furthe ...

ELSEVIER SCI LTD2022

Toward individualized medicine in stroke-The TiMeS project: Protocol of longitudinal, multi-modal, multi-domain study in stroke

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Olaf Blanke, Silvestro Micera, Friedhelm Christoph Hummel, Gabriel Girard, Takuya Morishita, Elena Beanato, Estelle Emeline Raffin, Sylvain Jean-François Harquel

Despite recent improvements, complete motor recovery occurs in < 15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments to each individual patient. However, there is a lack of knowledge concerning the preci ...

FRONTIERS MEDIA SA2022

An automatized method to determine latencies of motor-evoked potentials under physiological and pathophysiological conditions

Friedhelm Christoph Hummel, Takuya Morishita, Pierre Theopistos Vassiliadis, Andéol Geoffroy Cadic-Melchior, Claudia Bigoni

Background. Latencies of motor evoked potentials (MEPs) can provide insights into the motor neuronal pathways activated by transcranial magnetic stimulation. Notwithstanding its clinical relevance, accurate, unbiased methods to automatize latency detection ...

IOP Publishing Ltd2022

Evaluating reproducibility and subject-specificity of microstructure-informed connectivity

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Gabriel Girard, Elda Fischi Gomez, Gian Franco Piredda, Takuya Morishita, Elena Beanato

Tractography enables identifying and evaluating the healthy and diseased brain's white matter pathways from diffusion-weighted magnetic resonance imaging data. As previous evaluation studies have reported significant false-positive estimation biases, recen ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Gabriel Girard, Elda Fischi Gomez, Gian Franco Piredda, Thomas Yu, Takuya Morishita

Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values acqu ...

2022