Publications de Simone Romeni | EPFL Graph Search

Multimodal closed-loop strategies for gait recovery after spinal cord injury and stroke via the integration of robotics and neuromodulation

Restoring the ability to walk is a priority for individuals with neurological disorders or neurotraumatic injuries, given its significant impact on independence and quality of life. Multimodal closed-loop strategies that integrate robotic assistance and ne ...

2025

Biophysical characterization of the recording of unmyelinated and myelinated fiber activity with peripheral interfaces

Silvestro Micera, Simone Romeni

Unmyelinated fibers account for a remarkable fraction of the peripheral nervous system and their activity is linked to many autonomic and somatic functions. While electrical recording of such activity from human-sized peripheral nerves holds significant po ...

2025

Epidural electrical stimulation facilitates motor recovery in spinal cord injury involving the conus medullaris: A case study

Silvestro Micera, Simone Romeni

Background: Emerging research increasingly supports that epidural spinal cord electrical stimulation (EES) combined with neurorehabilitation can improve motor recovery in spinal cord injury (SCI) subjects. Patients with lesions involving the medullary cone ...

2025

Characterization of Machine Learning-Based Surrogate Models of Neural Activation Under Electrical Stimulation

Silvestro Micera, Simone Romeni

Bioelectromagnetics published by Wiley Periodicals LLC on behalf of Bioelectromagnetics Society.Electrical stimulation of peripheral nerves via implanted electrodes has been shown to be a promising approach to restore sensation, movement, and autonomic fun ...

2025

High-frequency epidural electrical stimulation reduces spasticity and facilitates walking recovery in patients with spinal cord injury

Silvestro Micera, Simone Romeni

Spinal cord injury (SCI) causes severe motor and sensory deficits, and there are currently no approved treatments for recovery. Nearly 70% of patients with SCI experience pathological muscle cocontraction and spasticity, accompanied by clinical signs such ...

AMER ASSOC ADVANCEMENT SCIENCE2025

Kinematic Similarity of Overground and Self-paced Omnidirectional Treadmill Walking in Healthy and Parkinsonian Subjects

Silvestro Micera, Simone Romeni

The use of self-paced omnidirectional treadmills equipped with body weight support and virtual reality environments in the clinical practice may allow the training of walking in safe and repeatable conditions across different pathologies. One premise for t ...

Springer Nature2025

Decoding electroencephalographic responses to visual stimuli compatible with electrical stimulation

Silvestro Micera, Simone Romeni, Laura Toni, Fiorenzo Artoni

Electrical stimulation of the visual nervous system could improve the quality of life of patients affected by acquired blindness by restoring some visual sensations, but requires careful optimization of stimulation parameters to produce useful perceptions. ...

Aip Publishing2024

A method and system for optimizing design, implantation, and stimulation protocols of electrodes stimulating the nervous system

Silvestro Micera, Simone Romeni

A method for optimizing at least one of a geometry, an implantation procedure, and/or stimulation protocol of one or more electrodes for an electrical stimulation of a target structure in a nervous system of a living being by a computer device, the method ...

2024

Biophysically accurate and machine learning-based surrogate models to optimize neuroprosthesis design and operation

Simone Romeni

Electrical stimulation of the nervous system has emerged as a promising assistive technology in case of many injuries and illnesses across various parts of the nervous system. In particular, the invasive neuromodulation of the peripheral nervous system see ...

EPFL2024

A computational model to design wide field-of-view optic nerve neuroprostheses

Silvestro Micera, Simone Romeni, Gabriele Marino

Retinal stimulation (RS) allows restoring vision in blind patients, but it covers only a narrow region of the visual field. Optic nerve stimulation (ONS) has the potential to produce visual perceptions spanning the whole visual field, but it produces very ...

CELL PRESS2024