Publications de Vijay Kumar Rana

Impact of Molecular Dynamics of Polyrotaxanes on Chondrocytes in Double-Network Supramolecular Hydrogels under Physiological Thermomechanical Stimulation

Dominique Pioletti, Theofanis Stampoultzis, Yanheng Guo, Vijay Kumar Rana

Hyaline cartilage, a soft tissue enriched with a dynamic extracellular matrix, manifests as a supramolecular system within load-bearing joints. At the same time, the challenge of cartilage repair through tissue engineering lies in replicating intricate cel ...

American Chemical Society2024

Development and Performance Evaluation of Hybrid Iono-organogels for Efficient Impact Mitigation

Dominique Pioletti, Pierre-Etienne Bourban, Vincent Marc Varanges, Vijay Kumar Rana

Dissipative materials are essential for mitigating impact in various automotive, aerospace, and sports equipment applications. This study investigates the efficiency of a novel hybrid iono-organogel in dissipating and absorbing impact energies. The gel con ...

American Chemical Society (ACS)2024

Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation

Dominique Pioletti, Theofanis Stampoultzis, Yanheng Guo, Ece Uslu, François Gorostidi, Vijay Kumar Rana

Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations as they inadequately cover the wound, fail to prevent fluid leakage, and increase the risk of infe ...

Amer Chemical Soc2023

Wet adhesive hydrogels to correct malacic trachea (tracheomalacia) A proof of concept

Dominique Pioletti, Nikolaos Stergiopoulos, Peyman Karami, Sokratis Anagnostopoulos, Ece Uslu, Vijay Kumar Rana

Tracheomalacia (TM) is a condition characterized by a weak tracheal cartilage and/or muscle, resulting in excessive collapse of the airway in the newborns. Current treatments including tracheal reconstruction, tracheoplasty, endo- and extra-luminal stents ...

CELL PRESS2023

Unraveling cartilage degeneration through synergistic effects of hydrostatic pressure and biomimetic temperature increase

Dominique Pioletti, Peyman Karami, Naser Nasrollahzadeh Mamaghani, Theofanis Stampoultzis, Yanheng Guo, Vijay Kumar Rana

Cartilage degeneration, typically viewed as an irreversible, vicious cycle, sees a significant reduction in two essential biophysical cues: the well-established hydrostatic pressure (HP) and the recently discovered transient temperature increase. Our study ...

Cell Press2023

NIR Light-Mediated Photocuring of Adhesive Hydrogels for Noninvasive Tissue Repair via Upconversion Optogenesis

Dominique Pioletti, Christophe Moser, Peyman Karami, Yanheng Guo, Antoine Vincent Boniface, Vijay Kumar Rana

The surgical treatments of injured soft tissues lead to further injury due to the use of sutures or the surgical routes, which need to be large enough to insert biomaterials for repair. In contrast, the use of low viscosity photopolymerizable hydrogels tha ...

American Chemical Society2022