Kim Do

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Publications associées (57)

N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial

Rolf Gruetter, Lijing Xin, Alessandra Griffa, Kim Do, Patric Hagmann

Mechanism-based treatments for schizophrenia are needed, and increasing evidence suggests that oxidative stress may be a target. Previous research has shown that N-acetylcysteine (NAC), an antioxidant and glutathione (GSH) precursor almost devoid of side e ...

2018

Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex

Rolf Gruetter, Lijing Xin, Kim Do

Recent studies have shown that cannabis may disrupt glutamate (Glu) signaling depressing Glu tone in frequent users. Current evidence have also consistently reported lower Glu-levels in various brain regions, particularly in the medial prefrontal cortex (m ...

Springer Verlag2018

An Add-On Trial With N-Acetyl-Cysteine (Nac) In Early Psychosis Patients: Towards Biomarker Guided Treatment

Rolf Gruetter, Lijing Xin, Kim Do

Oxford University Pres2018

Childhood Trauma Engages Oxidative Stress, Hippocampus Alterations, And Poorer Clinical Outcome In Early Psychosis Patients

Alessandra Griffa, Patric Hagmann, Kim Do

Oxford University Press2018

N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis

Rolf Gruetter, Lijing Xin, Kim Do

2018

Redox Dysregulation, Oligodendrocytes And White Matter Alterations In Schizophrenia

Lijing Xin, Alessandra Griffa, Patric Hagmann, Kim Do

Oxford University Press2018

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

Rolf Gruetter, Alberto Corcoba, Kim Do, João Miguel das Neves Duarte

Environmental stress can interact with genetic predisposition to increase the risk of developing psychopathology. In this work, we tested the hypothesis that social isolation stress interacts with impaired glutathione synthesis and have cumulative effects ...

Wiley-Blackwell2017