Properties of volume-sensitive Cl- channels in a human epithelial cell line
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This paper describes a 3D computation of an open channel flow with a sharp bend. The flow with a bend is characterized by generation of secondary current of the first kind due to the local unbalance of the centrifugal force and lateral pressure gradient. S ...
Understanding the functional dynamics of ligand-gated ion-channels (LGIC's) on the molecular level is the aim of this thesis. Members of the protein family of LGIC's are involved in the fast synaptic signal transmission and thereby play a central role in i ...
A generalization of Arikan's polar code construction using transformations of the form G(circle times n) where G is an l x l matrix is considered. Necessary and sufficient conditions are given for these transformations to ensure channel polarization. It is ...
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We developed a new non-invasive integrated microsystem for electrophysiological measurements on Xenopus laevis oocytes. The Xenopus oocyte is a well-known expression system for various kinds of ion channels that are of potential interest for drug screening ...
An apparatus for manipulating fluid samples comprises a micro-chip device having first and second covered channels, each channel having openings at both ends. The channels intersect to form a common intersection. Three of the openings of the channels are c ...
The membrane kinetics of human atrial myocytes as formulated by Courtemance, Ramierz and Nattel has been studied while focusing on its progression toward stationary solutions during long term repetitive stimulation. An algorithm is presented for finding th ...
Nicotinic acetylcholine receptors are heteropentameric ion channels that open upon activation to a single conducting state. The second transmembrane segments of each subunit were identified as channel-forming elements, but their respective contribution in ...
A rapid transformation of eicosapentaenoic acid is initiated upon disintegration of cells of the marine diatom Stephanopyxis turris. In contrast to any other fatty acid cleaving activity known, this diatom releases a blend of chlorinated C8-hydrocarbons in ...
We investigated the wound response of the commercially important red alga, Gracilaria chilensis, in order to obtain insight into its interaction with epiphytic pests. After wounding, the host releases free fatty acids as well as the hydroxylated eicosanoid ...
The subject of this thesis is the study of the structure and function of the human muscle nicotinic acetylcholine receptor (nAChR), which is a typical member of the large class of ligand-gated ion channels. Appropriate techniques, like site-directed mutage ...
