Propagation velocity kinetics and repolarization alternans in a free-behaving sheep model of pacing-induced atrial fibrillation
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In pacing-induced models of atrial fibrillation (AF) that mimic atrial high-frequency foci, the increase in AF susceptibility over time is not paralleled by any increase in dispersion of repolarization (DOR). Measurements of effective refractory periods (E ...
Introduction: It has been shown that repolarization alternans (Re-ALT), a beat-to-beat alternation in action potential duration, enhances dispersion of repolarization DOR above a critical heart rate and promotes susceptibility to ventricular arrhythmias. I ...
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In pacing-induced models of atrial fibrillation (AF) that mimic atrial high-frequency foci, the increase in AF susceptibility over time is not paralleled by any increase in dispersion of repolarization (DOR). Measurements of effective refractory periods (E ...
Atrial fibrillation is the most common sustained cardiac rhythm disturbance, increasing in prevalence with age. During the past 20 years, there has been a 66% increase in hospital admissions related to atrial fibrillation. Neither the natural history of at ...
One of the rhythm control strategies in atrial fibrillation management consists in the application of a brief single electrical shock to the atria. This electrical cardioversion does not always succeed, and the long-term success of this therapy is not suff ...
A method is described to determine the effect on the ECG of a reduced propagation velocity within an ischemic zone. The method was designed to change the activation sequence throughout the ventricles interactively, i.e. with a response time in the order of ...
For over a century, electrocardiology has been observing human cardiac activity through recordings of electrocardiograms (ECG). The potential differences derived from the nine electrodes of the standard 12-lead ECG, placed at their designated positions, ar ...
The propagation of electric activity inside a realistically-shaped, thick-walled model of the atria was studied. The membrane kinetics was based on the formulations of Courtemanche, Ramirez and Nattel. In spite of the assumed uniformity of all kinetics par ...
Doctor Macchi reported on the progress of an animal model study of electric propagation initiated by electric stimuli. Doctor Oostendorp first gave an introduction to the inverse problem of cardiac activation time mapping (ATM), the determination of the de ...
The most common type of sustained arrhythmia is atrial fibrillation (AF), affecting about 2% of the general population and 8% to 11% of the elderly, more than 65 years of age. The treatment of atrial arrythmia is still based on empirical considerations and ...