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Expression of the zebrafish gene hlx-1 in the prechordal plate and during CNS development

Publications associées (38)

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Combined function of HoxA and HoxB clusters in neural crest cells

Denis Duboule, Maxence Vieux-Rochas

The evolution of chordates was accompanied by critical anatomical innovations in craniofacial development, along with the emergence of neural crest cells. The potential of these cells to implement a craniofacial program in part depends upon the (non-)expre ...

Academic Press Inc Elsevier Science2013

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Severe spinal cord injury in humans leads to a progressive neuronal dysfunction in the chronic stage of the injury. This dysfunction is characterized by premature exhaustion of muscle activity during assisted locomotion, which is associated with the emerge ...

Oxford University Press2013

The gene uncx4.1 is a paired-type homeobox transcription factor, expressed during zebrafish embryonic development in branchial arches, somites, CNS and pronephric ducts. In particular, the expression at the somite level is detectable from 5ss stage and bec ...

Elsevier Science BV2009

Rostral and caudal pharyngeal arches share a common neural crest ground pattern

Denis Duboule

In vertebrates, face and throat structures, such as jaw, hyoid and thyroid cartilages develop from a rostrocaudal metameric series of pharyngeal arches, colonized by cranial neural crest cells (NCCs). Colinear Hox gene expression patterns underlie arch spe ...

2009

BACKGROUND: Notch signaling influences binary cell fate decisions in a variety of tissues. The Notch1 receptor is widely expressed during embryogenesis and is essential for embryonic development. Loss of global Notch1 function results in early embryonic le ...

2005

The first morphological sign of vertebrate postcranial body segmentation is the sequential production from posterior paraxial mesoderm of blocks of cells termed somites. Each of these embryonic structures is polarized along the anterior/posterior axis, a s ...

2005

Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate

Anne Grapin-Botton, Mithlesh Kumar

During embryonic development, organs arise along the gut tube as a series of buds in a stereotyped anterior-posterior (A-P) pattern. Using chick-quail chimeras and in vitro tissue recombination, we studied the interactions governing the. induction and main ...

2003

The mechanisms that guide progenitor cell fate and differentiation in the vertebrate central nervous system (CNS) are poorly understood. Gain-of-function experiments suggest that Notch signaling is involved in the early stages of mammalian neurogenesis. On ...

2002

Zebrafish lunatic fringe demarcates segmental boundaries

Andrew Charles Oates

Cell interactions involving Notch signaling are required for the demarcation of tissue boundaries in both invertebrate and vertebrate development. Members of the Fringe gene family encode β-1,3 N-acetyl-glucosaminyltransferases that function to refine the ...

2001

Multiple roles of mouse Numb in tuning developmental cell fates

Michel Aguet, Lukas Sommer

BACKGROUND: Notch signaling regulates multiple differentiation processes and cell fate decisions during both invertebrate and vertebrate development. Numb encodes an intracellular protein that was shown in Drosophila to antagonize Notch signaling at binary ...

2001